Research Output 1988 2019

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2019

Are there clinically relevant anatomical differences of the proximal femur in patients with mild dysplastic and primary hip osteoarthritis? - A CT-data based matched pairs cohort study

Innmann, M., Hasberg, S., Waldstein, W., Grammatopoulos, G., Gill, H., Pegg, E., Aldinger, P. R. & Merle, C., 10 Jun 2019, (Accepted/In press) In : Clinical Radiology.

Research output: Contribution to journalArticle

Copolymerization of Cyclic Phosphonate and Lactide: Synthetic Strategies toward Control of Amphiphilic Microstructure

Beament, J., Wolf, T., Markwart, J. C., Wurm, F. R., Jones, M. D. & Buchard, A., 2019, In : Macromolecules. 52, 3, p. 1220–1226 7 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Countershading in zebrafish results from an Asip1 controlled dorsoventral gradient of pigment cell differentiation.

Cal, L., Suarez-Bregua, P., Comesana, P., Owen, J., Braasch, I., Kelsh, R. N., Cerda-Reverter, J. & Rotllant, J., 5 Mar 2019, In : Scientific Reports. 9, 1, p. 1-13 13 p., 3449.

Research output: Contribution to journalArticle

Open Access
File

Dicer1 is required for pigment cell and craniofacial development in zebrafish.

Weiner, A., Scampoli, N., Steeman, T., Dooley, C. M., Busch-Nentwich, E., Kelsh, R. N. & Calcaterra, N., 30 Apr 2019, In : BBA - Gene Regulatory Mechanisms. 1862, 4, p. 472-485 14 p.

Research output: Contribution to journalArticle

Efficiently Generating Mixing by Combining Differing Small Amplitude Helical Geometries

Cookson, A., Doorly, D. & Sherwin, S., 27 Mar 2019, In : Fluids. 4, 2, p. 59-84 26 p.

Research output: Contribution to journalArticle

Open Access
File

Endothelin neurotransmitter signalling controls zebrafish social behaviour

Carreno-Gutierrez, H., Colanesi, S., Cooper, B., Kelsh, R. N., Reichmann, F., Young, A. & Norton, W., 28 Feb 2019, In : Scientific Reports. 9, 1, 3040.

Research output: Contribution to journalArticle

Open Access

Endothelin receptor Aa regulates proliferation and differentiation of Erb-dependent pigment progenitors in zebrafish

Camargo Sosa, K., Colanesi, S., Muller, J., Schulte-Mercker, S., Stemple, D., Patton, E. & Kelsh, R. N., 27 Feb 2019, In : Plos Genetics. 15, 2, p. e1007941

Research output: Contribution to journalArticle

Open Access
File

Ferroelectret materials and devices for energy harvesting applications

Zhang, Y., Bowen, C. R., Ghosh, S. K., Mandal, D., Khanbareh, H., Arafa, M. & Wan, C., 1 Mar 2019, In : Nano Energy. 57, p. 118-140 23 p.

Research output: Contribution to journalArticle

Mechanically robust cationic cellulose nanofibril 3D scaffolds with tuneable biomimetic porosity for cell culture

Courtenay, J. C., Filgueiras, J. G., Deazevedo, E. R., Jin, Y., Edler, K. J., Sharma, R. I. & Scott, J. L., 1 Jan 2019, In : Journal of Materials Chemistry B . 7, 1, p. 53-64 12 p.

Research output: Contribution to journalArticle

Open Access

Mice with a conditional deletion of Talpid3 (KIAA0586) - a model for Joubert Syndrome

Bashford, A. L. & Subramanian, V., 28 Mar 2019, In : The Journal of Pathology.

Research output: Contribution to journalArticle

Multi-locus sequence typing of Ixodes ricinus and its symbiont Candidatus Midichloria mitochondrii across Europe reveals evidence of local co-cladogenesis in Scotland

Al-Khafaji, A. M., Clegg, S. R., Pinder, A. C., Luu, L., Hansford, K. M., Seelig, F., Dinnis, R. E., Margos, G., Medlock, J. M., Feil, E. J., Darby, A. C., McGarry, J. W., Gilbert, L., Plantard, O., Sassera, D. & Makepeace, B. L., 1 Jan 2019, In : Ticks and Tick-Borne Diseases. 10, 1, p. 52-62 11 p.

Research output: Contribution to journalArticle

Operative and Radiographic Acetabular Component Orientation in Total Hip Replacement: Influence of Pelvic Orientation and Surgical Positioning Technique

Rutherford, M., O'Connor, J. D., Gill, H. S., Hill, J., Beverland, D., Lennon, A. B. & Dunne, N. J., 1 Feb 2019, In : Medical Engineering & Physics . 64, p. 7-14 8 p.

Research output: Contribution to journalArticle

Hip Replacement Arthroplasties
Ligaments
Pelvis
Regression Analysis
Research

Posterior Bearing Overhang Following Medial and Lateral Mobile Bearing Unicompartmental Knee Replacements: A prospective Cohort Study. Level 2 evidence

Martin, B., Pegg, E., Van Duren, B., Mohammad, H., Pandit, H., Mellon, S. J. & Murray, D., 16 Apr 2019, (Accepted/In press) In : Journal of Orthopaedic Research.

Research output: Contribution to journalArticle

Open Access

The Role of Vascular Endothelial Growth Factor in Systemic Sclerosis

Flower, V. A., Barratt, S. L., Ward, S. & Pauling, J. D., 2019, In : Current Rheumatology Reviews. 15, 2, p. 99-109

Research output: Contribution to journalArticle

Open Access
File
Systemic Scleroderma
Vascular Endothelial Growth Factor A
Protein Isoforms
Precision Medicine
Disease Management
2018

A comparative bioinformatic analysis of C9orf72

Iyer, S., Acharya, K. R. & Subramanian, V., 19 Feb 2018, In : PeerJ. 6, p. e4391

Research output: Contribution to journalArticle

Open Access
Neurodegenerative diseases
Bioinformatics
Computational Biology
bioinformatics
Introns
6 Citations (Scopus)

Advanced glycation end products modulate amyloidogenic APP processing and Tau phosphorylation: a mechanistic link between glycation and the development of Alzheimer’s disease

Batkulwar, K., Godbole, R., Banarjee, R., Kassaar, O., Williams, R. J. & Kulkarni, M., 16 May 2018, In : ACS Chemical Neuroscience. 9, 5, p. 1-37

Research output: Contribution to journalArticle

Open Access
File
Advanced Glycosylation End Products
Phosphorylation
Alzheimer Disease
Endopeptidases
Cathepsin B
7 Citations (Scopus)
Ring opening polymerization
Aluminum
polymerization
Ligands
aluminum
1 Citation (Scopus)

An intestinal paracellular pathway biased toward positively-charged macromolecules.

Almansour, K., Taverner, A., Turner, J., Eggleston, I. & Mrsny, R., 28 Oct 2018, In : Journal of Controlled Release. 288, p. 111-125 15 p.

Research output: Contribution to journalArticle

Claudin-2
Dextrans
Permeability
Myosin Light Chains
Peptides

A systems biology approach uncovers the core gene regulatory network governing iridophore fate choice from the neural crest.

Petratou, K., Subkhankulova, T., Lister, J., Schwetlick, H. & Kelsh, R. N., 4 Oct 2018, In : Plos Genetics. 14, 10, 32 p., e1007402.

Research output: Contribution to journalArticle

Open Access
2 Citations (Scopus)
Open Access
File
Lanthanoid Series Elements
Bearings (structural)
Thermodynamic properties
Polymerization
Nuclear magnetic resonance
3 Citations (Scopus)

C9orf72, a protein associated with amyotrophic lateral sclerosis (ALS) is a guanine nucleotide exchange factor

Iyer, S., Subramanian, V. & Acharya, K. R., 17 Oct 2018, In : PeerJ. 6, 29 p., e5815.

Research output: Contribution to journalArticle

Open Access

Characterisation and use of a functional Gadd45g bacterial artificial chromosome

Warr, N., May, J., Teboul, L., Suzuki, T., Asami, M., Perry, A., Wells, S. & Greenfield, A., 23 Nov 2018, In : Scientific Reports. 8, 1, 17318.

Research output: Contribution to journalArticle

Open Access

Continuous enzymatic hydrolysis of sugar beet pectin and L-arabinose recovery within an integrated biorefinery

Cárdenas-Fernández, M., Hamley-Bennett, C., Leak, D. J. & Lye, G. J., 1 Dec 2018, In : Bioresource Technology. 269, p. 195-202 8 p.

Research output: Contribution to journalArticle

Open Access
Sugar beets
Arabinose
Enzymatic hydrolysis
sugar beet
hydrolysis
1 Citation (Scopus)

Correction of pelvic adduction during total hip arthroplasty reduces variability in radiographic inclination: findings of a randomised controlled trial

O'Neill, C., Magill, P., Hill, J., Patterson, C., Molloy, D., Gill, H. & Beverland, D., 1 May 2018, In : Hip International. 28, 3, p. 240-245 6 p.

Research output: Contribution to journalArticle

Open Access
File
Arthroplasty
Hip
Randomized Controlled Trials
Operating Tables
Sacrum

Electrochemically Driven C-H Hydrogen Abstraction Processes with the Tetrachloro-Phthalimido-N-Oxyl (Cl4PINO) Catalyst

Marken, F., Buckingham, M. A., Bull, S., Cunningham, W., Buchard, A., Folli, A. & Murphy, D., 1 Aug 2018, In : Electroanalysis. 30, 8, p. 1706-1713

Research output: Contribution to journalArticle

Open Access
File
Hydrogen
Alcohols
Catalysts
Rate constants
Oxidation
1 Citation (Scopus)
Open Access
Cryoultramicrotomy
Embryoid Bodies
Organoids
Histological Techniques
Organogenesis

Endothelin receptor Aa regulates proliferation and differentiation of Erb-dependent pigment progenitors in zebrafish.

Camargo Sosa, K., Colanesi, S., Muller, J., Schulte-Mercker, S., Stemple, D., Patton, E. E. & Kelsh, R. N., 2018, In : bioRxiv.

Research output: Contribution to journalArticle

Open Access
6 Citations (Scopus)
Open Access

Gene drives accelerate evolution – but we need brakes

Perry, A., 5 Jul 2018, The Conversation.

Research output: Contribution to specialist publicationArticle

Open Access
File
1 Citation (Scopus)
Open Access
File
Neprilysin
Neurotensin
Protein Conformation
Enkephalins
Metalloproteases
5 Citations (Scopus)

Impulsive choice in mice lacking paternal expression of Grb10 suggests intragenomic conflict in behavior

Dent, C. L., Humby, T., Lewis, K., Ward, A., Fischer-Colbrie, R., Wilkinson, L. S., Wilkins, J. F. & Isles, A. R., 1 May 2018, In : Genetics. 209, 1, p. 233-239

Research output: Contribution to journalArticle

Open Access
4 Citations (Scopus)

Intestinal P-glycoprotein exports endocannabinoids to prevent inflammation and maintain homeostasis

Szabady, R., Louissaint, C., Lubben, A., Xie, B., Reeksting, S., Touhy, C., Demma, Z., Foley, S. E., Faherty, C. S., Llanos-Chea, A., Olive, A. J., Mrsny, R. & McCormick, B., 31 Aug 2018, In : Journal of Clinical Investigation. 128, 9, p. 4044-4056 13 p.

Research output: Contribution to journalArticle

Endocannabinoids
P-Glycoprotein
Neutrophils
Homeostasis
Inflammation
2 Citations (Scopus)

In vitro model for predicting bioavailability of subcutaneously injected monoclonal antibodies

Bown, H. K., Bonn, C., Yohe, S. T., Yadav, D. B., Patapoff, T. W., Daugherty, A. L. & Mrsny, R. J., 10 Mar 2018, In : Journal of Controlled Release. 273, p. 13-20 8 p.

Research output: Contribution to journalArticle

Open Access
File
Subcutaneous Injections
Biological Availability
Monoclonal Antibodies
Miniature Swine
Drug Compounding
3 Citations (Scopus)
Open Access
Validation Studies
Bone Density
Bone and Bones
Hydrochloric Acid
Torque

Lifestyle behaviours and perceived well-being in different fire service roles

Turner, P. J. F., Siddall, A. G., Stevenson, R. D. M., Standage, M. & Bilzon, J. L. J., 16 Nov 2018, In : Occupational Medicine. 68, 8, p. 537-543 7 p.

Research output: Contribution to journalArticle

Firefighters
Life Style
Occupational Groups
Emergencies
Health
1 Citation (Scopus)

Mechanism of CO 2 capture in nanostructured sodium amide encapsulated in porous silica

Tian, M., Buchard, A., Wells, S. A., Fang, Y., Torrente-murciano, L., Nearchou, A., Dong, Z., White, T. J., Sartbaeva, A. & Ting, V. P., 25 Sep 2018, In : Surface & Coatings Technology. 350, p. 227-233 7 p.

Research output: Contribution to journalArticle

Carbon Monoxide
Encapsulation
Amides
Silicon Dioxide
amides
3 Citations (Scopus)
Myosin Light Chains
Intestinal Mucosa
Phosphorylation
Tight Junctions
Peptides
1 Citation (Scopus)

Next generation in vitro liver model design: Combining a permeable polystyrene membrane with a transdifferentiated cell line

Luetchford, K. A., Wung, N., Argyle, I. S., Storm, M. P., Weston, S. D., Tosh, D. & Ellis, M. J., 1 Nov 2018, In : Journal of Membrane Science. 565, p. 425-438 14 p.

Research output: Contribution to journalArticle

Open Access
Polystyrenes
cultured cells
liver
Liver
polystyrene
1 Citation (Scopus)
Open Access
File
Heart-Assist Devices
Hydrodynamics
Dynamic analysis
Computational fluid dynamics
Shear stress

Over-expressed, N-terminally truncated BRAF is detected in the nucleus of cells with nuclear phosphorylated MEK and ERK

Hey, F., Andreadi, C., Noble, C., Patel, B., Jin, H., Kamata, T., Straatman, K., Luo, J., Balmanno, K., Jones, D. T. W., Collins, V. P., Cook, S. J., Caunt, C. J. & Pritchard, C., 20 Dec 2018, In : Heliyon. 4, 12, e01065.

Research output: Contribution to journalArticle

Open Access

Pelvic Positioning in the Supine Position Leads to More Consistent Cup Orientation after Total Hip Arthroplasty

Grammatopoulos, G., Gofton, W., Cochran, M., Dobransky, J., Carli, A., Abdelbary, H., Gill, H. & Beaule, P., 8 Oct 2018, In : The Bone & Joint Journal. 100-B, 10, p. 1280-1288

Research output: Contribution to journalArticle

Supine Position
Pelvis
Arthroplasty
Tacrine
Hip
2 Citations (Scopus)

Polymers from sugars and CS2: synthesis and ring-opening polymerisation of sulfur-containing monomers derived from 2-deoxy- d-ribose and d-xylose

López-vidal, E. M., Gregory, G. L., Kociok-Kohn, G. & Buchard, A., 7 Apr 2018, In : Polymer Chemistry. 9, p. 1577-1582

Research output: Contribution to journalArticle

Open Access
File
Xylose
Ribose
Ring opening polymerization
Sulfur
Sugars
3 Citations (Scopus)

Predicting ligand-free cell attachment on next generation cellulose-chitosan hydrogels

Johns, M., Bae, Y., Guimarães, F., Lanzoni, E. M., Costa, C. A., Murray, P., Deneke, C., Galembeck, F., Scott, J. & Sharma, R., 31 Jan 2018, In : ACS OMEGA. 3, 1, p. 937–945

Research output: Contribution to journalArticle

Open Access
Hydrogels
Chitosan
Cellulose
Ligands
Elastic moduli
Amyotrophic Lateral Sclerosis
Mutation
Proteins
Motor Neuron Disease
Missense Mutation
5 Citations (Scopus)

Recent Advances in Modified Cellulose for Tissue Culture Applications

Courtenay, J., Sharma, R. & Scott, J., 14 Mar 2018, In : Molecules. 23, 3, p. 1-20 20 p., 654.

Research output: Contribution to journalArticle

Open Access
Tissue culture
cellulose
Cellulose
Scaffolds
tissue engineering
1 Citation (Scopus)

Reducing the variability in apparent operative inclination during total hip arthroplasty. Findings of a prospective randomised controlled trial

O'Neill, C., Hill, J., Patterson, C., Molloy, D., Gill, H. & Beverland, D., 1 May 2018, In : Hip International. 28, 3, p. 234-239 6 p.

Research output: Contribution to journalArticle

Open Access
File
Arthroplasty
Hip
Randomized Controlled Trials
Translating
Reading

Spatiotemporal regulation of liver development by the Wnt/β-catenin pathway

Burke, Z. D., Reed, K. R., Yeh, S-W., Meniel, V., Sansom, O. J., Clarke, A. R. & Tosh, D., 9 Feb 2018, In : Scientific Reports. 8, 1, p. 1-9 9 p., 2735.

Research output: Contribution to journalArticle

Open Access
beta Catenin
Glutamate-Ammonia Ligase
Liver
Ammonia
Carbamoyl-Phosphate Synthase (Ammonia)