Research Output 1988 2020

2017
5 Citations (Scopus)

Cell surface dynamics and cellular distribution of endogenous FcRn

D'Hooghe, L., D Chalmers, A., Heywood, S. & Whitley, P., 17 Aug 2017, In : PLoS ONE. 12, 8, e0182695.

Research output: Contribution to journalArticle

Open Access
Immunoglobulin G
Endocytosis
endocytosis
recycling
albumins
13 Citations (Scopus)

Cervical spine injuries: a whole-body musculoskeletal model for the analysis of spinal loading

Cazzola, D., Holsgrove, T. P., Preatoni, E., Gill, H. S. & Trewartha, G., 4 Jan 2017, In : PLoS ONE. 12, 1, p. 1-24 24 p., e0169329.

Research output: Contribution to journalArticle

Open Access
cervical spine
Football
Spine
Wounds and Injuries
Computer Simulation

Cervical spine posture influences fracture patterns caused by impact loading

Agostinho Hernandez, B., Blackburn, J., Cazzola, D., Holsgrove, T., Gill, H. & Gheduzzi, S., Sep 2017.

Research output: Contribution to conferenceOther

Posture
Spine
Sports
Wounds and Injuries
Bone Cements
12 Citations (Scopus)

CO2-Driven stereochemical inversion of sugars to create thymidine-based polycarbonates by ring-opening polymerisation

Gregory, G. L., Hierons, E. M., Kociok-Kohn, G., Sharma, R. I. & Buchard, A., 14 Mar 2017, In : Polymer Chemistry. 8, 10, p. 1714-1721

Research output: Contribution to journalArticle

Open Access
polycarbonate
Carbonates
Ring opening polymerization
Polycarbonates
Sugars
Organoids
Drug Discovery
Colorectal Neoplasms
Biological Models
Drug Industry
10 Citations (Scopus)

Continuous production of bio-renewable, polymer-grade lactone monomers through Sn-β catalysed Baeyer-Villiger oxidation with H2O2

Yakabi, K., Mathieux, T., Milne, K., Lopez-Vidal, E. M., Buchard, A. & Hammond, C., 22 Sep 2017, In : ChemSusChem. 10, 18, p. 3652–3659

Research output: Contribution to journalArticle

Lactones
Polymers
polymer
Monomers
oxidation

Cumulative effects of occupational loading as a risk factor for hip pain in UK military personnel: Study Protocol of a Case Control Study

Coppack, R. J., Bilzon, J., Wills, A. K., McCurdie, I. M., Walton, D., Nicol, A. M. & Bennett, A. N., 12 Jun 2017, In : International Journal of Sports and Exercise Medicine. 3, 3, 11 p.

Research output: Contribution to journalArticle

Open Access
Military Personnel
Case-Control Studies
Hip
Pain
Population
13 Citations (Scopus)
60 Downloads (Pure)

Di-Zinc Aryl Complexes: CO2 Insertions and Applications in Polymerization Catalysis

Romain, C., Garden, J. A., Trott, G., Buchard, A., White, A. J. P. & Williams, C. K., 29 May 2017, In : Chemistry - A European Journal. 23 , 30, p. 7367–7376

Research output: Contribution to journalArticle

Open Access
File
Carbon Dioxide
Catalysis
Zinc
Polymerization
1-Propanol
7 Citations (Scopus)
100 Downloads (Pure)

Dual crosslinked pectin–alginate network as sustained release hydrophilic matrix for repaglinide

Awasthi, R., Kulkarni, G., Ramana, M. V., Pinto, T., Kikuchi, I. S., Ghisleni, D., de Souza Braga, M., De Bank, P. & Dua, K., Apr 2017, In : International Journal of Biological Macromolecules. 97, p. 721-732

Research output: Contribution to journalArticle

Open Access
File
repaglinide
Pharmaceutical Preparations
Tablets
Polymers
Excipients
fatty acid
physical property
acid
crystallinity
melting
3 Citations (Scopus)
76 Downloads (Pure)
Open Access
File
Surface roughness
Materials Testing
Chromium
Cobalt
Titanium
18 Downloads (Pure)

Establishing and validating an osteoporotic model using bovine tibia

Fletcher, J., Whitehouse, M., Gill, H. & Preatoni, E., Jul 2017. 1 p.

Research output: Contribution to conferencePaper

File

Establishing and validating an osteoporotic model using juvenile bovine tibiae

Fletcher, J., Williams, S., Whitehouse, M., Gill, H. & Preatoni, E., 2017, (Accepted/In press). 1 p.

Research output: Contribution to conferenceAbstract

23 Downloads (Pure)

Establishing optimum screw tightening to maximise pullout force in fracture fixation

Fletcher, J., Whitehouse, M., Gill, H. & Preatoni, E., Jul 2017. 1 p.

Research output: Contribution to conferencePaper

File

Establishing optimum screw tightening to maximise pullout force in fracture fixation

Fletcher, J., Williams, S., Whitehouse, M., Gill, H. & Preatoni, E., 2017, (Accepted/In press). 1 p.

Research output: Contribution to conferenceAbstract

31 Downloads (Pure)

Evaluating the appropriate screw fastening torque in cortical bone - A Validated finite element model

MacLeod, A., Polak-Krasna, K., Fletcher, J., Whitehouse, M., Preatoni, E. & Gill, H., Jul 2017. 1 p.

Research output: Contribution to conferencePaper

File
Bone
Torque
Stress relaxation
Fracture fixation
Screw threads

Evaluating the Screw Fastening Torque Required to Generate Appropriate Preload in Bone Fracture Fixation

MacLeod, A., Polak-Krasna, K., Fletcher, J. & Gill, H., 4 Sep 2017.

Research output: Contribution to conferencePoster

Fracture fixation
Bone
Torque

Gnawing at striping - how rodents evolve striped patterns

Kelsh, R. N. & Petratou, K., 1 Mar 2017, In : Pigment Cell & Melanoma Research. 30, 2, p. 181-182

Research output: Contribution to journalArticle

Open Access
14 Citations (Scopus)
57 Downloads (Pure)

Highly potent and isoform-selective dual-site-binding tankyrase/Wnt signaling inhibitors that increase cellular glucose uptake and have anti-proliferative activity

Nathubhai, A., Haikarainen, T., Koivunen, J., Murthy, S., Koumanov, F., Lloyd, M., Holman, G., Pihlajaniemi, T., Tosh, D., Lehtio, L. & Threadgill, M., 26 Jan 2017, In : Journal of Medicinal Chemistry. 60, 2, p. 814-820 7 p.

Research output: Contribution to journalArticle

Open Access
File
Tankyrases
Inhibitory Concentration 50
Protein Isoforms
Binding Sites
Glucose
4 Citations (Scopus)

Impact of anatomical placement of an accelerometer on prediction of physical activity energy expenditure in lower-limb amputees

Ladlow, P., Nightingale, T., McGuigan, M., Bennett, A. N., Phillip, R. & Bilzon, J., 5 Oct 2017, In : PLoS ONE. 12, 10, 15 p., e0185731.

Research output: Contribution to journalArticle

Open Access
Amputees
limbs (animal)
Accelerometers
energy expenditure
physical activity
2 Citations (Scopus)
40 Downloads (Pure)
Open Access
File
Amyloid Precursor Protein Secretases
Amyloid beta-Protein Precursor
Proteins
Alzheimer Disease
Luciferases

Insights and lessons from a scientific conference on non-invasive delivery of macromolecules

Savla, R., Mrsny, R. J., Park, K., Aubert, I. & Stamoran, C., 1 Jun 2017, In : Pharmaceutical Research. 34, 6, p. 1149-1151 3 p.

Research output: Contribution to journalComment/debate

Macromolecules
Patient Compliance
Pharmaceutical Preparations
Pipelines
Safety

Keynote Lecture: Future musculoskeletal healthcare challenges

Gill, H., 15 Sep 2017.

Research output: Contribution to conferencePaper

shear thinning
large eddy simulation
blood
turbulence
analogs
11 Citations (Scopus)

Macrophage Migration Inhibitory Factor is subjected to glucose modification and oxidation in Alzheimer's Disease

Kassaar, O., Pereira Morais, M., Xu, S., Adam, E. L., Chamberlain, R. C., Jenkins, B., James, T., Francis, P. T., Ward, S., Williams, R. J. & Van Den Elsen, J., 23 Feb 2017, In : Scientific Reports. 7, 42874.

Research output: Contribution to journalArticle

Open Access
Macrophage Migration-Inhibitory Factors
Alzheimer Disease
Glucose
Hyperglycemia
Aptitude

Non-linear strain predictions for bone screw fixation for developing a surgical decision aid

Polak-Krasna, K., MacLeod, A., Fletcher, J., Whitehouse, M., Preatoni, E. & Gill, H., 15 Sep 2017.

Research output: Contribution to conferencePaper

Bone Screws
Decision Support Techniques
Bone and Bones
Torque
Fracture Fixation
29 Downloads (Pure)
Open Access
File
Heart-Assist Devices
Shear stress
Blood
Hydrodynamics
Strain rate
Shear stress
Blood
Fluid dynamics
Strain rate
Numerical models
48 Citations (Scopus)

Nutrition for the ageing brain: towards evidence for an optimal diet

Vauzour, D., Camprubi-Robles, M., Miquel-Kergoat, S., Andres-Lacueva, C., Banati, D., Barberger-Gateau, P., Bowman, G., Carbelotto, L., Clarke, R., Hogervorst, E., Kiliaan, A., Lucca, U., Manach, C., Minihane, A-M., Mitchell, E. S., Perneczky, R., Perry, H., Roussel, A-M., Schuermans, J., Sijben, J. & 8 others, Spencer, J. PE., Thuret, S., van de Rest, O., Vandewoude, M., Wesnes, K., Williams, R. J., Williams, R. SB. & Ramirez, M., 1 May 2017, In : Ageing Research Reviews. 35, p. 222-240

Research output: Contribution to journalArticle

Open Access
Nutrition
Brain
Aging of materials
Diet
Cognition

Optimal pullout resistance is achieved when bone screws are inserted at 65-75% of the stripping torque

Fletcher, J., MacLeod, A., Polak-Kraśna, K., Whitehouse, M., Gill, H. & Preatoni, E., 10 Nov 2017, (Accepted/In press).

Research output: Contribution to conferenceAbstract

Optimal Pullout Resistance Is Achieved When Bone Screws Are Inserted At 65 To 75% Of The Stripping Torque

Fletcher, J., MacLeod, A., Polak-Kraśna, K., Williams, S., Whitehouse, M., Gill, H. & Preatoni, E., 17 Nov 2017, (Accepted/In press). 1 p.

Research output: Contribution to conferenceAbstract

Bone
Torque
Health
Economics
1 Citation (Scopus)
developmental biology
Developmental Biology
evolutionary biology
Genomics
genomics
4 Citations (Scopus)
63 Downloads (Pure)
Open Access
File
Firefighters
Sensitivity and Specificity
Aptitude
Task Performance and Analysis
36 Citations (Scopus)
78 Downloads (Pure)

Polymers from sugar: cyclic monomer synthesis, ring-opening polymerisation, material properties and applications

Gregory, G. L., López-Vidal, E. M. & Buchard, A., 27 Jan 2017, In : Chemical communications (Cambridge, England). 53, 14, p. 2198-2217

Research output: Contribution to journalArticle

Open Access
File
Ring opening polymerization
Sugars
Materials properties
Polymers
Monomers
16 Citations (Scopus)
Open Access
polycarbonate
Ribose
Carbonates
Ring opening polymerization
Polycarbonates
Sickle Cell Anemia
Femur
Thigh
Anatomy
Necrosis

Reducing ethical and financial costs in biomechanical research: is juvenile bovine bone the answer?

Fletcher, J., Williams, S., Whitehouse, M., Gill, H. & Preatoni, E., 2017, (Accepted/In press). 1 p.

Research output: Contribution to conferenceAbstract

9 Downloads (Pure)

Regional endocardial strains in the left ventricle enable more accurate assessment of acutely-evolving and chronic heart failure post-myocardial infarction

Odunmbaku-Mansell, O., Bruno, V. D., Sammut, E., Thomas, J., Ascione, R., Gill, H., Fraser, K. & Cookson, A., 18 Dec 2017, (Submitted).

Research output: Contribution to conferencePaper

File
Heart Ventricles
Heart Failure
Myocardial Infarction
Swine
Economic Inflation
42 Downloads (Pure)
Open Access
File
15 Citations (Scopus)
35 Downloads (Pure)

Salan Group 13 complexes – structural study and lactide polymerisation

Beament, J., Mahon, M., Buchard, A. & Jones, M., 7 Mar 2017, In : New Journal of Chemistry. 41, 5, p. 2198-2203

Research output: Contribution to journalArticle

Open Access
File
ethylenediamine
Ligands
Polymerization
Ring opening polymerization
Molecular weight distribution
2 Citations (Scopus)
89 Downloads (Pure)

Semiconductor technology in protein kinase research and drug discovery: sensing a revolution

Bhalla, N., Di Lorenzo, M., Estrela, P. & Pula, G., Feb 2017, In : Drug Discovery Today. 22, 2, p. 204-209 6 p.

Research output: Contribution to journalArticle

Open Access
File
Semiconductors
Drug Discovery
Protein Kinase Inhibitors
Protein Kinases
Cell Physiological Phenomena

Smoking status and physical fitness during initial military training

Siddall, A. G., Bilzon, J. L. J., Thompson, D., Greeves, J., Izard, R. & Stokes, K. A., 1 Apr 2017, In : Occupational Medicine. 67, 3, p. 205-210 6 p.

Research output: Contribution to journalArticle

Physical Fitness
Smoking
Linear Models
Population
21 Citations (Scopus)

Sonic hedgehog signaling in limb development

Tickle, C. & Towers, M., 28 Feb 2017, In : Frontiers in Cell and Developmental Biology. 5, FEB, 14.

Research output: Contribution to journalReview article

Open Access
Hedgehogs
Limb Buds
Extremities
Mesoderm
Vertebrates
4 Citations (Scopus)

Sox10 contributes to the balance of fate choice in dorsal root ganglion progenitors

Delfino-Machin, M., Madelaine, R., Buscolin, G., Nikaido, M., Colanesi, S., Camargo Sosa, K., Law, E. W. P., Toppo, S., Blader, P., Tiso, N. & Kelsh, R. N., 1 Mar 2017, In : PLoS ONE. 12, 3, e0172947.

Research output: Contribution to journalArticle

Open Access
9 Citations (Scopus)
91 Downloads (Pure)

Structural evidence of quercetin multi-target bioactivity: A reverse virtual screening strategy

Carvalho, D., Paulino, M., Polticelli, F., Arredondo, F., Williams, R. J. & Abin-Carriquiry, J. A., 19 Jun 2017, In : European Journal of Pharmaceutical Sciences. 106, p. 393-403 11 p.

Research output: Contribution to journalArticle

Open Access
File
Quercetin
Proteins
Phosphatidylinositol 3-Kinase
Poly(ADP-ribose) Polymerases
Xanthine Oxidase
10 Citations (Scopus)

Structural insights into human angiogenin variants implicated in Parkinson's disease and Amyotrophic Lateral Sclerosis

Bradshaw, W. J., Rehman, S., Pham, T. T. K., Thiyagarajan, N., Lee, R. L., Subramanian, V. & Acharya, K. R., 8 Feb 2017, In : Scientific Reports. 7, p. 1-10 10 p., 41996.

Research output: Contribution to journalArticle

Open Access
Amyotrophic Lateral Sclerosis
Parkinson Disease
Cell Line
Pancreatic Ribonuclease
Ribonucleases

Study of impact loading on the cervical spine using digital image correlation

Agostinho Hernandez, B., Dyke, L., Gill, R. & Gheduzzi, S., 5 Sep 2017.

Research output: Contribution to conferencePaper

32 Citations (Scopus)
107 Downloads (Pure)

Surface modified cellulose scaffolds for tissue engineering

Courtenay, J. C., Johns, M. A., Galembeck, F., Deneke, C., Lanzoni, E. M., Costa, C. A., Scott, J. L. & Sharma, R. I., Jan 2017, In : Cellulose. 24, 1, p. 253-267 15 p.

Research output: Contribution to journalArticle

Open Access
File
Scaffolds (biology)
Tissue engineering
Cellulose
oxidized cellulose
Acetobacter
2 Citations (Scopus)

The design and manufacture of a personalized liner for lower limb amputees

Dhokia, V., Bilzon, J., Seminati, E., Canepa Talamas, D. A., Young, M. & Mitchell, W., 2017, In : Procedia CIRP. 60, p. 476-481 5 p.

Research output: Contribution to journalArticle

Open Access
Prosthetics
Machining
Artificial limbs
Silicon
Cryogenics