Research Output 1988 2019

2017
15 Downloads (Pure)

Establishing and validating an osteoporotic model using bovine tibia

Fletcher, J., Whitehouse, M., Gill, H. & Preatoni, E., Jul 2017. 1 p.

Research output: Contribution to conferencePaper

File

Establishing and validating an osteoporotic model using juvenile bovine tibiae

Fletcher, J., Williams, S., Whitehouse, M., Gill, H. & Preatoni, E., 2017, (Accepted/In press). 1 p.

Research output: Contribution to conferenceAbstract

Establishing optimum screw tightening to maximise pullout force in fracture fixation

Fletcher, J., Williams, S., Whitehouse, M., Gill, H. & Preatoni, E., 2017, (Accepted/In press). 1 p.

Research output: Contribution to conferenceAbstract

21 Downloads (Pure)

Establishing optimum screw tightening to maximise pullout force in fracture fixation

Fletcher, J., Whitehouse, M., Gill, H. & Preatoni, E., Jul 2017. 1 p.

Research output: Contribution to conferencePaper

File
28 Downloads (Pure)

Evaluating the appropriate screw fastening torque in cortical bone - A Validated finite element model

MacLeod, A., Polak-Krasna, K., Fletcher, J., Whitehouse, M., Preatoni, E. & Gill, H., Jul 2017. 1 p.

Research output: Contribution to conferencePaper

File
Bone
Torque
Stress relaxation
Fracture fixation
Screw threads

Evaluating the Screw Fastening Torque Required to Generate Appropriate Preload in Bone Fracture Fixation

MacLeod, A., Polak-Krasna, K., Fletcher, J. & Gill, H., 4 Sep 2017.

Research output: Contribution to conferencePoster

Fracture fixation
Bone
Torque

Gnawing at striping - how rodents evolve striped patterns

Kelsh, R. N. & Petratou, K., 1 Mar 2017, In : Pigment Cell & Melanoma Research. 30, 2, p. 181-182

Research output: Contribution to journalArticle

Open Access
14 Citations (Scopus)
39 Downloads (Pure)

Highly potent and isoform-selective dual-site-binding tankyrase/Wnt signaling inhibitors that increase cellular glucose uptake and have anti-proliferative activity

Nathubhai, A., Haikarainen, T., Koivunen, J., Murthy, S., Koumanov, F., Lloyd, M., Holman, G., Pihlajaniemi, T., Tosh, D., Lehtio, L. & Threadgill, M., 26 Jan 2017, In : Journal of Medicinal Chemistry. 60, 2, p. 814-820 7 p.

Research output: Contribution to journalArticle

Open Access
File
Tankyrases
Inhibitory Concentration 50
Protein Isoforms
Binding Sites
Glucose
4 Citations (Scopus)

Impact of anatomical placement of an accelerometer on prediction of physical activity energy expenditure in lower-limb amputees

Ladlow, P., Nightingale, T., McGuigan, M., Bennett, A. N., Phillip, R. & Bilzon, J., 5 Oct 2017, In : PLoS ONE. 12, 10, 15 p., e0185731.

Research output: Contribution to journalArticle

Open Access
Amputees
limbs (animal)
Accelerometers
energy expenditure
physical activity
2 Citations (Scopus)
36 Downloads (Pure)
Open Access
File
Amyloid Precursor Protein Secretases
Amyloid beta-Protein Precursor
Proteins
Alzheimer Disease
Luciferases

Insights and lessons from a scientific conference on non-invasive delivery of macromolecules

Savla, R., Mrsny, R. J., Park, K., Aubert, I. & Stamoran, C., 1 Jun 2017, In : Pharmaceutical Research. 34, 6, p. 1149-1151 3 p.

Research output: Contribution to journalComment/debate

Macromolecules
Patient Compliance
Pharmaceutical Preparations
Pipelines
Safety

Keynote Lecture: Future musculoskeletal healthcare challenges

Gill, H., 15 Sep 2017.

Research output: Contribution to conferencePaper

shear thinning
large eddy simulation
blood
turbulence
analogs
11 Citations (Scopus)

Macrophage Migration Inhibitory Factor is subjected to glucose modification and oxidation in Alzheimer's Disease

Kassaar, O., Pereira Morais, M., Xu, S., Adam, E. L., Chamberlain, R. C., Jenkins, B., James, T., Francis, P. T., Ward, S., Williams, R. J. & Van Den Elsen, J., 23 Feb 2017, In : Scientific Reports. 7, 42874.

Research output: Contribution to journalArticle

Open Access
Macrophage Migration-Inhibitory Factors
Alzheimer Disease
Glucose
Hyperglycemia
Aptitude

Non-linear strain predictions for bone screw fixation for developing a surgical decision aid

Polak-Krasna, K., MacLeod, A., Fletcher, J., Whitehouse, M., Preatoni, E. & Gill, H., 15 Sep 2017.

Research output: Contribution to conferencePaper

Bone Screws
Decision Support Techniques
Bone and Bones
Torque
Fracture Fixation
24 Downloads (Pure)
Open Access
File
Heart-Assist Devices
Shear stress
Blood
Hydrodynamics
Strain rate
Shear stress
Blood
Fluid dynamics
Strain rate
Numerical models
41 Citations (Scopus)

Nutrition for the ageing brain: towards evidence for an optimal diet

Vauzour, D., Camprubi-Robles, M., Miquel-Kergoat, S., Andres-Lacueva, C., Banati, D., Barberger-Gateau, P., Bowman, G., Carbelotto, L., Clarke, R., Hogervorst, E., Kiliaan, A., Lucca, U., Manach, C., Minihane, A-M., Mitchell, E. S., Perneczky, R., Perry, H., Roussel, A-M., Schuermans, J., Sijben, J. & 8 others, Spencer, J. PE., Thuret, S., van de Rest, O., Vandewoude, M., Wesnes, K., Williams, R. J., Williams, R. SB. & Ramirez, M., 1 May 2017, In : Ageing Research Reviews. 35, p. 222-240

Research output: Contribution to journalArticle

Open Access
Nutrition
Brain
Aging of materials
Diet
Cognition

Optimal pullout resistance is achieved when bone screws are inserted at 65-75% of the stripping torque

Fletcher, J., MacLeod, A., Polak-Kraśna, K., Whitehouse, M., Gill, H. & Preatoni, E., 10 Nov 2017, (Accepted/In press).

Research output: Contribution to conferenceAbstract

Optimal Pullout Resistance Is Achieved When Bone Screws Are Inserted At 65 To 75% Of The Stripping Torque

Fletcher, J., MacLeod, A., Polak-Kraśna, K., Williams, S., Whitehouse, M., Gill, H. & Preatoni, E., 17 Nov 2017, (Accepted/In press). 1 p.

Research output: Contribution to conferenceAbstract

Bone
Torque
Health
Economics
1 Citation (Scopus)
developmental biology
Developmental Biology
evolutionary biology
Genomics
genomics
2 Citations (Scopus)
52 Downloads (Pure)
Open Access
File
Firefighters
Sensitivity and Specificity
Aptitude
Task Performance and Analysis
33 Citations (Scopus)
52 Downloads (Pure)

Polymers from sugar: cyclic monomer synthesis, ring-opening polymerisation, material properties and applications

Gregory, G. L., López-Vidal, E. M. & Buchard, A., 27 Jan 2017, In : Chemical communications (Cambridge, England). 53, 14, p. 2198-2217

Research output: Contribution to journalArticle

Open Access
File
Ring opening polymerization
Sugars
Materials properties
Polymers
Monomers
16 Citations (Scopus)
Open Access
polycarbonate
Ribose
Carbonates
Ring opening polymerization
Polycarbonates
Sickle Cell Anemia
Femur
Thigh
Anatomy
Necrosis

Reducing ethical and financial costs in biomechanical research: is juvenile bovine bone the answer?

Fletcher, J., Williams, S., Whitehouse, M., Gill, H. & Preatoni, E., 2017, (Accepted/In press). 1 p.

Research output: Contribution to conferenceAbstract

7 Downloads (Pure)

Regional endocardial strains in the left ventricle enable more accurate assessment of acutely-evolving and chronic heart failure post-myocardial infarction

Odunmbaku-Mansell, O., Bruno, V. D., Sammut, E., Thomas, J., Ascione, R., Gill, H., Fraser, K. & Cookson, A., 18 Dec 2017, (Submitted).

Research output: Contribution to conferencePaper

File
Heart Ventricles
Heart Failure
Myocardial Infarction
Swine
Economic Inflation
37 Downloads (Pure)

Residuum volume and shape assessment after lower limb amputation: validity and reliability of a new structured light 3D scanner

Seminati, E., Canepa Talamas, D. A., Dhokia, V., Young, M., Twiste, M. & Bilzon, J., 8 May 2017, p. 316.

Research output: Contribution to conferenceAbstract

Open Access
File
14 Citations (Scopus)
20 Downloads (Pure)

Salan Group 13 complexes – structural study and lactide polymerisation

Beament, J., Mahon, M., Buchard, A. & Jones, M., 7 Mar 2017, In : New Journal of Chemistry. 41, 5, p. 2198-2203

Research output: Contribution to journalArticle

Open Access
File
ethylenediamine
Ligands
Polymerization
Ring opening polymerization
Molecular weight distribution
2 Citations (Scopus)
68 Downloads (Pure)

Semiconductor technology in protein kinase research and drug discovery: sensing a revolution

Bhalla, N., Di Lorenzo, M., Estrela, P. & Pula, G., Feb 2017, In : Drug Discovery Today. 22, 2, p. 204-209 6 p.

Research output: Contribution to journalArticle

Open Access
File
Semiconductors
Drug Discovery
Protein Kinase Inhibitors
Protein Kinases
Cell Physiological Phenomena

Smoking status and physical fitness during initial military training

Siddall, A. G., Bilzon, J. L. J., Thompson, D., Greeves, J., Izard, R. & Stokes, K. A., 1 Apr 2017, In : Occupational Medicine. 67, 3, p. 205-210 6 p.

Research output: Contribution to journalArticle

Physical Fitness
Smoking
Linear Models
Population
19 Citations (Scopus)

Sonic hedgehog signaling in limb development

Tickle, C. & Towers, M., 28 Feb 2017, In : Frontiers in Cell and Developmental Biology. 5, FEB, 14.

Research output: Contribution to journalReview article

Open Access
Hedgehogs
Limb Buds
Extremities
Mesoderm
Vertebrates
4 Citations (Scopus)

Sox10 contributes to the balance of fate choice in dorsal root ganglion progenitors

Delfino-Machin, M., Madelaine, R., Buscolin, G., Nikaido, M., Colanesi, S., Camargo Sosa, K., Law, E. W. P., Toppo, S., Blader, P., Tiso, N. & Kelsh, R. N., 1 Mar 2017, In : PLoS ONE. 12, 3, e0172947.

Research output: Contribution to journalArticle

Open Access
9 Citations (Scopus)
72 Downloads (Pure)

Structural evidence of quercetin multi-target bioactivity: A reverse virtual screening strategy

Carvalho, D., Paulino, M., Polticelli, F., Arredondo, F., Williams, R. J. & Abin-Carriquiry, J. A., 19 Jun 2017, In : European Journal of Pharmaceutical Sciences. 106, p. 393-403 11 p.

Research output: Contribution to journalArticle

Open Access
File
Quercetin
Proteins
Phosphatidylinositol 3-Kinase
Poly(ADP-ribose) Polymerases
Xanthine Oxidase
10 Citations (Scopus)

Structural insights into human angiogenin variants implicated in Parkinson's disease and Amyotrophic Lateral Sclerosis

Bradshaw, W. J., Rehman, S., Pham, T. T. K., Thiyagarajan, N., Lee, R. L., Subramanian, V. & Acharya, K. R., 8 Feb 2017, In : Scientific Reports. 7, p. 1-10 10 p., 41996.

Research output: Contribution to journalArticle

Open Access
Amyotrophic Lateral Sclerosis
Parkinson Disease
Cell Line
Pancreatic Ribonuclease
Ribonucleases
31 Citations (Scopus)
84 Downloads (Pure)

Surface modified cellulose scaffolds for tissue engineering

Courtenay, J. C., Johns, M. A., Galembeck, F., Deneke, C., Lanzoni, E. M., Costa, C. A., Scott, J. L. & Sharma, R. I., Jan 2017, In : Cellulose. 24, 1, p. 253-267 15 p.

Research output: Contribution to journalArticle

Open Access
File
Scaffolds (biology)
Tissue engineering
Cellulose
oxidized cellulose
Acetobacter
2 Citations (Scopus)

The design and manufacture of a personalized liner for lower limb amputees

Dhokia, V., Bilzon, J., Seminati, E., Canepa Talamas, D. A., Young, M. & Mitchell, W., 2017, In : Procedia CIRP. 60, p. 476-481 5 p.

Research output: Contribution to journalArticle

Open Access
Prosthetics
Machining
Artificial limbs
Silicon
Cryogenics
4 Citations (Scopus)
55 Downloads (Pure)

The effect of ozone gas sterilization on the properties and cell compatibility of electrospun polycaprolactone scaffolds

Rediguieri, C., De Bank, P., Zanin, M. H. A., Leo, P., Cerize, N. N. P., de Oliveira, A. M. & Pinto, T., 30 Jul 2017, In : Journal of Biomaterials Science, Polymer Edition. 28, 16, p. 1918-1934 17 p.

Research output: Contribution to journalArticle

Open Access
File
Polycaprolactone
Ozone
Scaffolds (biology)
Scaffolds
Gases
12 Downloads (Pure)

The efficacy of rotational control designs in promoting torsional stability of hip fracture fixation

Gosiewski, J., Holsgrove, T. & Gill, H., 4 May 2017, In : Bone and Joint Research. 6, 5, p. 270-276

Research output: Contribution to journalArticle

Open Access
File
Fracture fixation
Bone Substitutes
Fracture Fixation
Hip Fractures
Bolts

The mathematics of mixing for understanding and controlling fluid mechanics in vascular prostheses

Cookson, A., Doorly, D. J. & Sherwin, S. J., Jul 2017.

Research output: Contribution to conferenceAbstract

1 Citation (Scopus)
22 Downloads (Pure)

The Role of Ubiquitination and Hepatocyte Growth Factor-Regulated Tyrosine Kinase Substrate in the Degradation of the Adrenomedullin Type I Receptor

Ward, S., Roux, B., Bauer, C., McNeish, A. & Cottrell, G., 28 Sep 2017, In : Open Access Scientific Reports. 7, 1, p. 1-18 18 p., 12389.

Research output: Contribution to journalArticle

Open Access
File
Receptor Activity-Modifying Protein 2
Calcitonin Receptor-Like Protein
Adrenomedullin
Ubiquitination
Adrenomedullin Receptors

Time resolved amplified FRET identifies protein kinase B activation state as a marker for poor prognosis in clear cell renal cell carcinoma

Miles, J., Applebee, C., Leboucher, P., Lopez-Fernandez, S., Lee, D-J., Guarch, R., Ward, S., Parker, P., Lopez, J. & Larijani, B., 1 Dec 2017, In : BBA Clinical. 8, p. 97-102 14 p.

Research output: Contribution to journalArticle

Open Access
Proto-Oncogene Proteins c-akt
Renal Cell Carcinoma
Neoplasms
Immunohistochemistry
Activation Analysis

Use of contrast agents on polymeric materials

Hossein Zadeh Zaribaf, P., Gill, H. & Pegg, E., 8 Feb 2017.

Research output: Contribution to conferencePaper

Contrast Media
Polymers
X rays
Knee prostheses
Biocompatible Materials

Validated cemented socket model for optimising acetabular fixation

Gosiewski, J., Gheduzzi, S. & Gill, H., Sep 2017.

Research output: Contribution to conferencePaper

Pelvis
Delivery of Health Care
Sacroiliac Joint
Finite Element Analysis
Bone Remodeling
17 Downloads (Pure)

Validated Cemented Socket Model for Optimising Acetabular Fixation

Gosiewski, J., Gheduzzi, S. & Gill, H., Jul 2017.

Research output: Contribution to conferencePaper

File
Jigs
Surgery
Composite materials
Finite element method
Ultrahigh molecular weight polyethylenes
7 Citations (Scopus)
37 Downloads (Pure)

Validity and reliability of a novel 3D scanner for assessment of the shape and volume of amputees’ residual limb models

Seminati, E., Canepa Talamas, D., Young, M., Twiste, M., Dhokia, V. & Bilzon, J., 8 Sep 2017, PLoS ONE, 12, 9, p. 0184498 16 p.

Research output: Contribution to specialist publicationArticle

Open Access
File
Amputees
Residual Volume
Reproducibility of Results
Extremities
Lasers
69 Downloads (Pure)

Vascular Regenerative Surgery: Promised Land for Tissue Engineers?

Fortunato, T., De Bank, P. & Pula, G., 3 Jun 2017, In : International Journal of Stem Cell Research and Transplantation. 5, 2, p. 268-276

Research output: Contribution to journalArticle

Open Access
File
Cell- and Tissue-Based Therapy
Blood Vessels
Biocompatible Materials
Cardiovascular Diseases
Induced Pluripotent Stem Cells
1 Citation (Scopus)
41 Downloads (Pure)
Open Access
File
Adult Stem Cells
Zebrafish
Stem cells
Pigments
Stem Cells
1 Citation (Scopus)
10 Downloads (Pure)
Open Access
File
Tin
initiators
Zirconium
Amines
amines