Research Output

2010

Genetic dissection of differential signaling threshold requirements for the Wnt/β-Catenin pathway in vivo

Buchert, M., Athineos, D., Abud, H. E., Burke, Z. D., Faux, M. C., Samuel, M. S., Jarnicki, A. G., Winbanks, C. E., Newton, I. P., Meniel, V. S., Suzuki, H., Stacker, S. A., Nathke, I. S., Tosh, D., Huelsken, J., Clarke, A. R., Heath, J. K., Sansom, O. J. & Ernst, M., 15 Jan 2010, In : Plos Genetics. 6, 1, e1000816.

Research output: Contribution to journalArticle

File
61 Citations (Scopus)
113 Downloads (Pure)

Hepatic progenitor cells

Sangan, C. B. & Tosh, D., Nov 2010, In : Cell and Tissue Research. 342, 2, p. 131-137 7 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Hollow Fiber Membrane Bioreactor Technology for Tissue Engineering and Stem Cell Therapy

Ye, H., Cui, Z. F., Ellis, M. J., Macedo, H. & Mantalaris, A., 9 Jul 2010, Chemical and Biochemical Transformations in Membrane Systems. Elsevier, Vol. 3. p. 213-227 15 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Citation (Scopus)

Human cardiac tissue induces transdifferentiation of adult stem cells towards cardiomyocytes

Peran, M., Marchal, J. A., Lopez, E., Jimenez-Navarro, M., Boulaiz, H., Rodriguez-Serrano, F., Carrillo, E., Sanchez-Espin, G., De Teresa, E., Tosh, D. & Aranega, A., May 2010, In : Cytotherapy. 12, 3, p. 332-337 6 p.

Research output: Contribution to journalArticle

44 Citations (Scopus)

Human RASSF7 regulates the microtubule cytoskeleton and is required for spindle formation, Aurora B activation and chromosomal congression during mitosis

Recino, A., Sherwood, V., Flaxman, A., Cooper, WN., Latif, F., Ward, A. & Chalmers, A. D., 1 Sep 2010, In : Biochemical Journal. 430, 2, p. 207-213 7 p.

Research output: Contribution to journalArticle

Open Access
21 Citations (Scopus)
73 Downloads (Pure)

Iminophosphorane-based [P2N2] rhodium complexes: synthesis, reactivity, and application in catalysed transfer hydrogenation of polar bonds

Buchard, A., Payet, E., Auffrant, A., Goff, X. L. & Floch, P. L., 2010, In : New Journal of Chemistry. 34, 12, p. 2943-2949 7 p.

Research output: Contribution to journalArticle

Open Access
File
12 Citations (Scopus)
141 Downloads (Pure)

Iminophosphorane neodymium(III) complexes as efficient initiators for lactide polymerization

Buchard, A., Platel, R. H., Auffrant, A., Le Goff, X. F., Le Floch, P. & Williams, C. K., 15 Jun 2010, In : Organometallics. 29, 13, p. 2892-2900 9 p.

Research output: Contribution to journalArticle

70 Citations (Scopus)

Interplay between hydrido/dihydrogen and amine/amido ligands in ruthenium-catalyzed transfer hydrogenation of ketones

Picot, A., Dyer, H., Buchard, A., Auffrant, A., Vendier, L., Le Floch, P. & Sabo-Etienne, S., 22 Jan 2010, In : Inorganic Chemistry. 49, 4, p. 1310-1312 3 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)

Mouse Emi2 as a distinctive regulatory hub in second meiotic metaphase

Suzuki, T., Suzuki, E., Yoshida, N., Kubo, A., Li, H., Okuda, E., Amanai, M. & Perry, A. C. F., 1 Oct 2010, In : Development. 137, 19, p. 3281-3291 11 p.

Research output: Contribution to journalArticle

49 Citations (Scopus)

Neuromuscular function following prolonged load carriage on level and downhill gradients

Blacker, S. D., Fallowfield, J. L., Bilzon, J. L. J. & Willems, M. E. T., 1 Aug 2010, In : Aviation Space and Environmental Medicine. 81, 8, p. 745-753 9 p.

Research output: Contribution to journalArticle

28 Citations (Scopus)

Post-culture treatment protocols for PLGA membrane scaffolds

Ellis, M. J., Forsey, R. & Chaudhuri, J. B., 1 Feb 2010, In : Biotechnology Letters. 32, 2, p. 215-222 8 p.

Research output: Contribution to journalArticle

RASSF7: a new possible therapeutic cancer target?

Recino, A., Flaxman, A., Sherwood, V., Cooper, W., Ward, A., Latif, F. & Chalmers, A. D., Feb 2010, In : Genetics Research. 92, 1, p. 71-72 2 p.

Research output: Contribution to journalArticle

RASSF7 Regulates Microtubules During Mitosis

Chalmers, A., 2010.

Research output: Contribution to conferencePaper

Retinoic acid signaling positively regulates liver specification by inducing wnt2bb gene expression in Medaka

Negishi, T., Nagai, Y., Asaoka, Y., Ohno, M., Namae, M., Mitani, H., Sasaki, T., Shimizu, N., Terai, S., Sakajda, I., Kondoh, H., Katada, T., Furutani-Seiki, M. & Nishina, H., Oct 2010, In : Hepatology. 51, 3, p. 1037-1045 9 p.

Research output: Contribution to journalArticle

21 Citations (Scopus)

Simvastatin release from poly(lactide-co-glycolide) membrane scaffolds

Rashidi, H., Ellis, M. J., Cartmell, S. H. & Chaudhuri, J. B., Dec 2010, In : Polymers. 2, 4, p. 709-718 10 p.

Research output: Contribution to journalArticle

Open Access
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5 Citations (Scopus)
120 Downloads (Pure)

The chromatoblast concept - evidence from zebrafish genetics

Kelsh, R. N., 2010.

Research output: Contribution to conferencePaper

The LIM protein Ajuba is required for ciliogenesis and left-right axis determination in medaka

Nagai, Y., Asaoka, Y., Namae, M., Saito, K., Momose, H., Mitani, H., Furutani-Seiki, M., Katada, T. & Nishina, H., 11 Jun 2010, In : Biochemical and Biophysical Research Communications. 396, 4, p. 887-893 7 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

The N-terminal RASSF family: a new group of Ras-association-domain-containing proteins, with emerging links to cancer formation

Sherwood, V., Recino, A., Jeffries, A., Ward, A. & Chalmers, A. D., 2010, In : Biochemical Journal. 425, 2, p. 303-311 9 p.

Research output: Contribution to journalReview article

File
65 Citations (Scopus)
141 Downloads (Pure)

The role of Cdx2 in Barrett's metaplasia

Colleypriest, B. J., Farrant, J. M., Slack, J. M. W. & Tosh, D., Apr 2010, In : Biochemical Society Transactions. 38, 2, p. 364-369 6 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)

The role of scaffold proteins in JNK signalling

Engstrom, W., Ward, A. & Moorwood, K., Feb 2010, In : Cell Proliferation. 43, 1, p. 56-66 11 p.

Research output: Contribution to journalReview article

39 Citations (Scopus)

Three-dimensional culture systems for the expansion of pluripotent embryonic stem cells

Storm, M. P., Orchard, C. B., Bone, H. K., Chaudhuri, J. B. & Welham, M. J., 1 Nov 2010, In : Biotechnology and Bioengineering. 107, 4, p. 683-695 13 p.

Research output: Contribution to journalArticle

56 Citations (Scopus)
2009

An in vitro study of electrically active hydroxyapatite-barium titanate ceramics using Saos-2 cells

Baxter, F., Turner, I. G., Bowen, C. R., Gittings, J. P. & Chaudhuri, J. B., Aug 2009, In : Journal of Materials Science: Materials in Medicine. 20, 8, p. 1697-1708 12 p.

Research output: Contribution to journalArticle

44 Citations (Scopus)

Cdx genes, inflammation and the pathogenesis of Barrett's metaplasia

Colleypriest, B. J., Palmer, R. M., Ward, S. G. & Tosh, D., Jul 2009, In : Trends in Molecular Medicine. 15, 7, p. 313-322 10 p.

Research output: Contribution to journalArticle

24 Citations (Scopus)

Characterization of the phosphoinositide 3-kinase-dependent transcriptome in murine embryonic stem cells: identification of novel regulators of pluripotency

Storm, M. P., Kumpfmueller, B., Thompson, B., Kolde, R., Vilo, J., Hummel, O., Schulz, H. & Welham, M. J., Apr 2009, In : Stem Cells. 27, 4, p. 764-775 12 p.

Research output: Contribution to journalArticle

44 Citations (Scopus)

Chromium (iii)-bis(iminophosphoranyl)methanido complexes: synthesis, X-ray crystal structures and catalytic ethylene oligomerization

Klemps, C., Buchard, A., Houdard, R., Auffrant, A., Mezailles, N., Le Goff, X. F., Ricard, L., Saussine, L., Magna, L. & Le Floch, P., 2009, In : New Journal of Chemistry. 33, 8, p. 1748-1752 5 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)

Coordination of tetradentate X2N2 (X = P, S, O) ligands to iron(II) metal center and catalytic application in the transfer hydrogenation of ketones

Buchard, A., Heuclin, H., Auffrant, A., Le Goff, X. F. & Le Floch, P., 2009, In : Dalton Transactions. 2009, 9, p. 1659-1667 9 p.

Research output: Contribution to journalArticle

41 Citations (Scopus)

Distinct roles for isoforms of the catalytic subunit of class-IA PI3K in the regulation of behaviour of murine embryonic stem cells

Kingham, E. & Welham, M., 2009, In : Journal of Cell Science. 122, 13, p. 2311-2321 11 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)

First neodymium(III) alkyl-carbene complex based on bis(iminophosphoranyl) ligands

Buchard, A., Auffrant, A., Ricard, L., Le Goff, X. F., Platel, R. H., Williams, C. K. & Le Floch, P., 2009, In : Dalton Transactions. 2009, 46, p. 10219-10222 4 p.

Research output: Contribution to journalArticle

42 Citations (Scopus)

Formation of a human-derived fat tissue layer in PDLLGA hollow fibre scaffolds for adipocyte tissue engineering

Morgan, S. M., Ainsworth, B. J., Kanczler, J. M., Babister, J. C., Chaudhuri, J. B. & Oreffo, R. O. C., Apr 2009, In : Biomaterials. 30, 10, p. 1910-1917 8 p.

Research output: Contribution to journalArticle

28 Citations (Scopus)

Generation of hepatocyte-like cells from in vitro transdifferentiated human fetal pancreas

Sumitran-Holgersson, S., Nowak, G., Thowfeequ, S., Begum, S., Joshi, M., Jaksch, M., Kjaeldgaard, A., Jorns, C., Ericzon, B. G. & Tosh, D., 1 Feb 2009, In : Cell Transplantation. 18, 2, p. 183-193 11 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

How does inflammation cause Barrett's metaplasia?

Colleypriest, B. J., Ward, S. G. & Tosh, D., Dec 2009, In : Current Opinion in Pharmacology. 9, 6, p. 721-726 6 p.

Research output: Contribution to journalArticle

40 Citations (Scopus)

Influence of timing of postexercise carbohydrate-protein ingestion on selected immune indices

Costa, R. J. S., Oliver, S. J., Laing, S. J., Walters, R., Bilzon, J. L. J. & Walsh, N. P., 1 Jan 2009, In : International Journal of Sport Nutrition and Exercise Metabolism. 19, 4, p. 366-384 19 p.

Research output: Contribution to journalArticle

34 Citations (Scopus)

Involvement of GSK-3 in regulation of murine embryonic stem cell self-renewal revealed by a series of bisindolylmaleimides

Bone, H. K., Damiano, T., Bartlett, S., Perry, A., Letchford, J., Ripoli, Y. S., Nelson, A. S. & Welham, M. J., 30 Jan 2009, In : Chemistry & Biology. 16, 1, p. 15-27 13 p.

Research output: Contribution to journalArticle

49 Citations (Scopus)

Liver zonation occurs through a β-catenin–dependent, c-Myc–independent mechanism

Burke, Z. D., Reed, K. R., Phesse, T. J., Sansom, O. J., Clarke, A. R. & Tosh, D., Jun 2009, In : Gastroenterology. 136, 7, p. 2316-2324e3 9 p.

Research output: Contribution to journalArticle

95 Citations (Scopus)

Mathematical modelling of fibre-enhanced perfusion inside a tissue-engineering bioreactor

Whittaker, R. J., Booth, R., Dyson, R., Bailey, C., Parsons Chini, L., Naire, S., Payvandi, S., Rong, Z., Woollard, H., Cummings, L. J., Waters, S. L., Mawasse, L., Chaudhuri, J. B., Ellis, M. J., Michael, V., Kuiper, N. J. & Cartmell, S., 2009, In : Journal of Theoretical Biology. 256, 4, p. 533-546 14 p.

Research output: Contribution to journalArticle

35 Citations (Scopus)

Melanocytes, modeling and maths - do we really understand differentiation?

Greenhill, E., Rocco, A., Nikaido, M. & Kelsh, R. N., 2009, In : Pigment Cell & Melanoma Research. 22, 5, p. 21

Research output: Contribution to journalArticle

Mixing through stirring of steady flow in small amplitude helical tubes

Cookson, A. N., Doorly, D. J. & Sherwin, S. J., Apr 2009, In : Annals of Biomedical Engineering. 37, 4, p. 710-721 12 p.

Research output: Contribution to journalArticle

39 Citations (Scopus)

New sources of β-cells for treating diabetes

Saha, S., Tosh, D. & Hardikar, A. A., Jul 2009, In : Journal of Endocrinology. 202, 1, p. 13-16 4 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)

One night of sleep deprivation decreases treadmill endurance performance

Oliver, S. J., Costa, R. J. S., Walsh, N. P., Laing, S. J. & Bilzon, J. L. J., 30 Sep 2009, In : European Journal of Applied Physiology. 107, 2, p. 155-161 7 p.

Research output: Contribution to journalArticle

93 Citations (Scopus)

Polymeric scaffolds for regenerative medicine

De Bank, P., Jones, M. & Ellis, M., 23 Dec 2009, Macroporous Polymers: Production Properties and Biotechnological/Biomedical Applications. Mattiasson, B., Kumar, A. & Galaev, I. Y. (eds.). CRC Press, p. 467-495 29 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Citation (Scopus)

Stripes and belly-spots: a review of pigment cell morphogenesis in vertebrates

Kelsh, R. N., Harris, M. L., Colanesi, S. & Erickson, C. A., 2009, In : Seminars in Cell & Developmental Biology. 20, 1, p. 90-104

Research output: Contribution to journalArticle

113 Citations (Scopus)

The novel RASSF6 and RASSF10 candidate tumour suppressor genes are frequently epigenetically inactivated in childhood leukaemias

Hesson, L. B., Dunwell, T. L., Cooper, W. N., Catchpoole, D., Brini, A. T., Chiaramonte, R., Griffiths, M., Chalmers, A. D., Maher, E. R. & Latif, F., 1 Jul 2009, In : Molecular Cancer. 8, 42

Research output: Contribution to journalArticle

File
81 Citations (Scopus)
88 Downloads (Pure)

Validity of DNA analysis to determine cell numbers in tissue engineering scaffolds

Forsey, R. W. & Chaudhuri, J. B., 2009, In : Biotechnology Letters. 31, 6, p. 819-823 5 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)
2008

A mixed phosphine−iminophosphorane tetradentate ligand: Synthesis, coordination to group 10 metal centers, and use as catalyst in Suzuki−Miyaura coupling

Buchard, A., Komly, B., Auffrant, A., Le Goff, X. F. & Floch, P. L., 7 Aug 2008, In : Organometallics. 27, 17, p. 4380-4385 6 p.

Research output: Contribution to journalArticle

23 Citations (Scopus)

An evolutionarily conserved intronic region controls the spatiotemporal expression of the transcription factor Sox10

Dutton, J. R., Antonellis, A., Carney, T. J., Rodriguez, F. S. L. M., Pavan, W. J., Ward, A. & Kelsh, R. N., 2008, In : BMC Developmental Biology. 8, 1, p. 105

Research output: Contribution to journalMeeting abstract

File
65 Citations (Scopus)
91 Downloads (Pure)

A Novel Method to Engineer Large ex vivo Neo-Tissue

Gribbon, C. & De Bank, P., Jul 2008, (Unpublished).

Research output: Contribution to conferencePoster

B-catenin deficiency, but not Myc deletion, suppresses the immediate phenotypes of APC loss in the liver

Reed, K. R., Athineos, D., Meniel, V. S., Wilkins, J. A., Ridgway, R. A., Burke, Z. D., Muncan, V., Clarke, A. R. & Sansom, O. J., 2008, In : Proceedings of the National Academy of Sciences of the United States of America. 105, 48, p. 18919-18923 5 p.

Research output: Contribution to journalArticle

51 Citations (Scopus)

Cell/Microparticle Aggregates – A Novel Method to Engineer Large ex vivo Neo-Tissue

Gribbon, C. & De Bank, P., 2008, In : European Cells and Materials. 16, S3, p. 56 1 p.

Research output: Contribution to journalMeeting abstract

Open Access

Effect of Polyvinyl Alcohol and Sodium Hypochlorite on Porosity and Hydrophilicity of PLGA Hollow Fibre Membrane Scaffolds

Meneghello, G., Ainsworth, B., Perera, S., Chaudhuri, J., Ellis, M. & De Bank, P., Dec 2008, (Unpublished).

Research output: Contribution to conferencePoster

Effect of polyvinyl alcohol and sodium hypochlorite on porosity and mechanical properties of PLGA hollow fibre membrane scaffolds

Meneghello, G., Ainsworth, B., De Bank, P., Ellis, M. J. & Chaudhuri, J., Jul 2008, In : European Cells and Materials. 16, S3, p. 82 1 p.

Research output: Contribution to journalMeeting abstract

Open Access
1 Citation (Scopus)