Research Output

Article

Formation of a polarised primitive endoderm layer in embryoid bodies requires Fgfr/Erk signalling

Doughton, G., Wei, J., Tapon, N., Welham, M. J. & Chalmers, A. D., 21 Apr 2014, In : PLoS ONE. 9, 4, e95434.

Research output: Contribution to journalArticle

Open Access
6 Citations (Scopus)
46 Downloads (Pure)

Full-term mouse development by abolishing Zn2+-dependent metaphase II arrest without Ca2+ release

Suzuki, T., Yoshida, N., Suzuki, E., Okuda, E. & Perry, A. C. F., 15 Aug 2010, In : Development. 137, 16, p. 2659-2669 11 p.

Research output: Contribution to journalArticle

55 Citations (Scopus)

Functional and mental health status of United Kingdom military amputees post-rehabilitation

Ladlow, P., Phillip, R., Etherington, J., Coppack, R., Bilzon, J., McGuigan, M. P. & Bennett, A. N., 1 Nov 2015, In : Archives of Physical Medicine and Rehabilitation. 96, 11, p. 2048-2054 7 p.

Research output: Contribution to journalArticle

Open Access
17 Citations (Scopus)

Functional constraints on SoxE proteins in neural crest development: the importance of differential expression for evolution of protein activity

Lee, E. M., Yuan, T., Ballim, R. D., Nguyen, K., Kelsh, R. N., Medeiros, D. M. & McCauley, D. W., 1 Oct 2016, In : Developmental Biology. 418, 1, p. 166-178

Research output: Contribution to journalArticle

Open Access
File
6 Citations (Scopus)
132 Downloads (Pure)

Functional ESCRT machinery is required for constitutive recycling of claudin-1 and maintenance of polarity in vertebrate epithelial cells

Dukes, J. D., Fish, L., Richardson, J. D., Blaikley, E., Burns, S., Caunt, C. J., Chalmers, A. D. & Whitley, P., 1 Sep 2011, In : Molecular Biology of the Cell. 22, 17, p. 3192-3205 14 p.

Research output: Contribution to journalArticle

Open Access
40 Citations (Scopus)
83 Downloads (Pure)

Functional nasal morphology of chimaerid fishes.

Kelsh, R., Sep 2013, In : Journal of Morphology. 274, 9, p. 987-1009 12 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

Gene drives accelerate evolution – but we need brakes

Perry, A., 5 Jul 2018, The Conversation.

Research output: Contribution to specialist publicationArticle

Generation of hepatocyte-like cells from in vitro transdifferentiated human fetal pancreas

Sumitran-Holgersson, S., Nowak, G., Thowfeequ, S., Begum, S., Joshi, M., Jaksch, M., Kjaeldgaard, A., Jorns, C., Ericzon, B. G. & Tosh, D., 1 Feb 2009, In : Cell Transplantation. 18, 2, p. 183-193 11 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

Genetic ablation of PI3Kγ results in defective IL-17RA signalling in T lymphocytes and increased IL-17 levels

Harris, S. J., Ciuclan, L., Finan, P. M., Wymann, M. P., Walker, C., Westwick, J., Ward, S. G. & Thomas, M. J., Dec 2012, In : European Journal of Immunology. 42, 12, p. 3394-3404 11 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Genetic dissection of differential signaling threshold requirements for the Wnt/β-Catenin pathway in vivo

Buchert, M., Athineos, D., Abud, H. E., Burke, Z. D., Faux, M. C., Samuel, M. S., Jarnicki, A. G., Winbanks, C. E., Newton, I. P., Meniel, V. S., Suzuki, H., Stacker, S. A., Nathke, I. S., Tosh, D., Huelsken, J., Clarke, A. R., Heath, J. K., Sansom, O. J. & Ernst, M., 15 Jan 2010, In : Plos Genetics. 6, 1, e1000816.

Research output: Contribution to journalArticle

File
61 Citations (Scopus)
125 Downloads (Pure)

Genetic regulation of pigment cell differentiation

Greenhill, E. & Kelsh, R. N., 2005, In : Pigment Cell Research. 18, Supplement 1, p. 41

Research output: Contribution to journalArticle

Genomic regions regulating imprinting and insulin-like growth factor-II promoter 3 activity in transgenics: novel enhancer and silencer elements

Ward, A., Fisher, R., Richardson, L., Pooler, J. A., Squire, S., Bates, P., Shaposhnikov, R., Hayward, N., Thurston, M. & Graham, C. F., Feb 1997, In : Genes and Function. 1, 1, p. 25-36 12 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)

Geographic variation in breeding system and environment predicts melanin-based plumage ornamentation of male and female Kentish plovers

Argüelles Ticó, A., Kupper, C., Kelsh, R. N., Kosztolányi, A., Szekely, T. & van Dijk, R. E., Jan 2016, In : Behavioral Ecology and Sociobiology. 70, 1, p. 49-60

Research output: Contribution to journalArticle

File
11 Citations (Scopus)
131 Downloads (Pure)

Gnawing at striping - how rodents evolve striped patterns

Kelsh, R. N. & Petratou, K., 1 Mar 2017, In : Pigment Cell & Melanoma Research. 30, 2, p. 181-182

Research output: Contribution to journalArticle

Open Access
Open Access
24 Downloads (Pure)

Harnessing Plasticity in an Amine-Borane as a Piezoelectric and Pyroelectric Flexible Film

Zhang, Y., Hopkins, M. A., Liptrot, D. J., Khanbareh, H., Groen, P., Zhou, X., Zhang, D., Bao, Y., Zhou, K., Bowen, C. R. & Carbery, D. R., 11 May 2020, In : Angewandte Chemie - International Edition. 59, 20, p. 7808-7812 5 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Hepatic progenitor cells

Sangan, C. B. & Tosh, D., Nov 2010, In : Cell and Tissue Research. 342, 2, p. 131-137 7 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Hepatocyte-ductal transdifferentiation is mediated by reciprocal repression of SOX9 and C/EBPα

O'Neill, K. E., Thowfeequ, S., Li, W-C., Eberhard, D., Dutton, J. R., Tosh, D. & Slack, J. M. W., 22 Sep 2014, In : Cellular Reprogramming. 16, 5, p. 314-323 10 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Highly potent and isoform-selective dual-site-binding tankyrase/Wnt signaling inhibitors that increase cellular glucose uptake and have anti-proliferative activity

Nathubhai, A., Haikarainen, T., Koivunen, J., Murthy, S., Koumanov, F., Lloyd, M., Holman, G., Pihlajaniemi, T., Tosh, D., Lehtio, L. & Threadgill, M., 26 Jan 2017, In : Journal of Medicinal Chemistry. 60, 2, p. 814-820 7 p.

Research output: Contribution to journalArticle

Open Access
File
26 Citations (Scopus)
138 Downloads (Pure)

High plasma insulin-like growth factor-II and low lipid content in transgenic mice: measurements of lipid metabolism

Da Costa, T. H., Williamson, D. H., Ward, A., Bates, P., Fisher, R., Richardson, L., Hill, D. J., Robinson, I. C. & Graham, C. F., Dec 1994, In : Journal of Endocrinology. 143, 3, p. 433-9 7 p.

Research output: Contribution to journalArticle

High resolution crystal structure of substrate-free human neprilysin

Moss, S., Subramanian, V. & Acharya, K. R., 1 Oct 2018, In : Journal of Structural Biology. 204, 1, p. 19-25 7 p.

Research output: Contribution to journalArticle

Open Access
File
7 Citations (Scopus)
58 Downloads (Pure)

High-resolution crystal structures of the botulinum neurotoxin binding domains from subtypes A5 and A6

Davies, J. R., Britton, A., Liu, S. M. & Acharya, K. R., 1 Aug 2020, In : FEBS Open Bio. 10, 8, p. 1474-1481 8 p.

Research output: Contribution to journalArticle

Open Access

Hippo pathway elements co-localize with occludin: a possible sensor system in pancreatic epithelial cells

Santos Cravo, A., Carter, E., Erkan, M., Harvey, E., Furutani-Seiki, M. & Mrsny, R., 15 Jul 2015, In : Tissue Barriers. 3, 3, p. 1-35 35 p., e1037948.

Research output: Contribution to journalArticle

Open Access
7 Citations (Scopus)
67 Downloads (Pure)

HNF1B variants associate with promoter methylation and regulate gene networks activated in prostate and ovarian cancer

Ross-Adams, H., Ball, S., Lawrenson, K., Halim, S., Russell, R., Wells, C., Strand, S. H., Ørntoft, T. F., Larson, M., Armasu, S., Massie, C. E., Asim, M., Mortensen, M. M., Borre, M., Woodfine, K., Warren, A. Y., Lamb, A. D., Kay, J., Whitaker, H., Ramos-Montoya, A. & 8 others, Murrell, A., Sørensen, K. D., Fridley, B. L., Goode, E. L., Gayther, S. A., Masters, J., Neal, D. E. & Mills, I. G., 9 Oct 2016, In : Oncotarget. 7, 46, p. 74734-74746 13 p.

Research output: Contribution to journalArticle

Open Access
24 Citations (Scopus)

Hollow fiber bioreactors for In Vivo-like mammalian tissue culture

Storm, M. P., Sorrell, I., Shipley, R., Regan, S., Luetchford, K. A., Sathish, J., Webb, S. & Ellis, M. J., 26 May 2016, In : Journal of Visualized Experiments. 2016, 111, e53431.

Research output: Contribution to journalArticle

Open Access
9 Citations (Scopus)

Hollow fibre membrane bioreactors for tissue engineering applications

Wung, N., Acott, S. M., Tosh, D. & Ellis, M. J., 27 Jul 2014, In : Biotechnology Letters. 36, 12, p. 2357-2366 10 p.

Research output: Contribution to journalArticle

Open Access
File
24 Citations (Scopus)
168 Downloads (Pure)

How does inflammation cause Barrett's metaplasia?

Colleypriest, B. J., Ward, S. G. & Tosh, D., Dec 2009, In : Current Opinion in Pharmacology. 9, 6, p. 721-726 6 p.

Research output: Contribution to journalArticle

40 Citations (Scopus)

How the embryo makes a limb: determination, polarity and identity

Tickle, C., Oct 2015, In : Journal Of Anatomy. 227, 4, p. 418-430

Research output: Contribution to journalArticle

37 Citations (Scopus)

Human bone derived cell culture on PLGA flat sheet membranes of different lactide: Glycolide ratio

Ellis, M. J. & Chaudhuri, J. B., 2008, In : Biotechnology and Bioengineering. 101, 2, p. 369-377 9 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)

Human Breast Cancer Cells Demonstrate Electrical Excitability

Ribeiro, M., Elghajiji, A., Fraser, S. P., Burke, Z., Tosh, D., Djamgoz, M. B. A. & Rocha, P., 30 Apr 2020, In : Frontiers in Neuroscience. 14, 404.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)

Human cardiac tissue induces transdifferentiation of adult stem cells towards cardiomyocytes

Peran, M., Marchal, J. A., Lopez, E., Jimenez-Navarro, M., Boulaiz, H., Rodriguez-Serrano, F., Carrillo, E., Sanchez-Espin, G., De Teresa, E., Tosh, D. & Aranega, A., May 2010, In : Cytotherapy. 12, 3, p. 332-337 6 p.

Research output: Contribution to journalArticle

44 Citations (Scopus)

Human growth-differentiation factor 3 (hGDF3): developmental regulation in human teratocarcinoma cell lines and expression in primary testicular germ cell tumours

Caricasole, A. A., van Schaik, R. H., Zeinstra, L. M., Wierikx, C. D., van Gurp, R. J., van den Pol, M., Looijenga, L. H., Oosterhuis, J. W., Pera, M. F., Ward, A., de Bruijn, I., Kramer, P., de Jong, F. H. & van den Eijnden-van Raaij, A. J., 8 Jan 1998, In : Oncogene. 16, 1, p. 95-103 9 p.

Research output: Contribution to journalArticle

53 Citations (Scopus)

Human RASSF7 regulates the microtubule cytoskeleton and is required for spindle formation, Aurora B activation and chromosomal congression during mitosis

Recino, A., Sherwood, V., Flaxman, A., Cooper, WN., Latif, F., Ward, A. & Chalmers, A. D., 1 Sep 2010, In : Biochemical Journal. 430, 2, p. 207-213 7 p.

Research output: Contribution to journalArticle

Open Access
21 Citations (Scopus)
73 Downloads (Pure)

Hydrodynamic rocking disc electrode study of the TEMPO-mediated catalytic oxidation of primary alcohols

Ahn, S. Y., Fisher, A. C., Buchard, A., Bull, S. D., Bond, A. M. & Marken, F., Sep 2016, In : Electroanalysis. 28, 9, p. 2093-2103

Research output: Contribution to journalArticle

Open Access
File
4 Citations (Scopus)
115 Downloads (Pure)

Hydrophobization of Cellulose Nanocrystals for Aqueous Colloidal Suspensions and Gels

Nigmatullin, R., Johns, M. A., Muñoz-García, J. C., Gabrielli, V., Schmitt, J., Angulo, J., Khimyak, Y. Z., Scott, J. L., Edler, K. J. & Eichhorn, S. J., 11 May 2020, In : Biomacromolecules. 21, 5, p. 1812-1823 12 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)
Open Access

Identification of cis-regulatory elements in the upstream regions of zebrafish runx3 gene through an in silico analysis: Implications for function.

Simoes, B., Conceição, N., Kelsh, R. & Cancela, M. L., Aug 2014, In : Journal of Applied Ichthyology. 30, 4, p. 661-670 10 p.

Research output: Contribution to journalArticle

Open Access
File
1 Citation (Scopus)
302 Downloads (Pure)

IGF-II ameliorates the dystrophic phenotype and coordinately down-regulates programmed cell death

Smith, J., Goldsmith, C., Ward, A. & LeDieu, R., Nov 2000, In : Cell Death and Differentiation. 7, 11, p. 1109-18 10 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)

Iminophosphorane-based [P2N2] rhodium complexes: synthesis, reactivity, and application in catalysed transfer hydrogenation of polar bonds

Buchard, A., Payet, E., Auffrant, A., Goff, X. L. & Floch, P. L., 2010, In : New Journal of Chemistry. 34, 12, p. 2943-2949 7 p.

Research output: Contribution to journalArticle

Open Access
File
12 Citations (Scopus)
154 Downloads (Pure)

Iminophosphorane neodymium(III) complexes as efficient initiators for lactide polymerization

Buchard, A., Platel, R. H., Auffrant, A., Le Goff, X. F., Le Floch, P. & Williams, C. K., 15 Jun 2010, In : Organometallics. 29, 13, p. 2892-2900 9 p.

Research output: Contribution to journalArticle

71 Citations (Scopus)

Impact of anatomical placement of an accelerometer on prediction of physical activity energy expenditure in lower-limb amputees

Ladlow, P., Nightingale, T., McGuigan, M., Bennett, A. N., Phillip, R. & Bilzon, J., 5 Oct 2017, In : PLoS ONE. 12, 10, 15 p., e0185731.

Research output: Contribution to journalArticle

Open Access
6 Citations (Scopus)

Impact of muscle glycogen availability on the capacity for repeated exercise in man

Alghannam, A., Jedrzejewski, D., Tweddle, M. G., Gribble, H., Bilzon, J., Thompson, D., Tsintzas, K. & Betts, J. A., Jan 2016, In : Medicine & Science in Sports & Exercise. 48, 1, p. 123-131

Research output: Contribution to journalArticle

Open Access
File
21 Citations (Scopus)
317 Downloads (Pure)

Impulsive choice in mice lacking paternal expression of Grb10 suggests intragenomic conflict in behavior

Dent, C. L., Humby, T., Lewis, K., Ward, A., Fischer-Colbrie, R., Wilkinson, L. S., Wilkins, J. F. & Isles, A. R., 1 May 2018, In : Genetics. 209, 1, p. 233-239 7 p.

Research output: Contribution to journalArticle

Open Access
8 Citations (Scopus)

Incidence and predictive factors of problems after fixation of trochanteric hip fractures with sliding hip screw or intramedullary devices

Page, P. R. J., Field, M. H., Vetharajan, N., Smith, A., Duggleby, L., Cazzola, D., Whitehouse, M. R. & Gill, R., 14 Sep 2020, In : Hip International.

Research output: Contribution to journalArticle

Open Access
File
4 Citations (Scopus)
85 Downloads (Pure)

Increased platelet adhesion and thrombus formation in a mouse model of Alzheimer's disease

Canobbio, I., Visconte, C., Oliviero, B., Guidetti, G., Zara, M., Pula, G. & Torti, M., Dec 2016, In : Cellular Signalling. 28, 12, p. 1863-1871

Research output: Contribution to journalArticle

Open Access
File
17 Citations (Scopus)
173 Downloads (Pure)

Influence of consciousness, muscle action and activity on medial condyle translation after Oxford unicompartmental knee replacement

Pegg, E. C., Bare, J., Gill, H. S., Pandit, H. G., O'Connor, J. J., Murray, D. W. & Price, A. J., 1 Dec 2015, In : The Knee. 22, 6, p. 646-652 7 p.

Research output: Contribution to journalArticle

File
3 Citations (Scopus)
259 Downloads (Pure)
11 Citations (Scopus)
Open Access
File
11 Downloads (Pure)

Influence of timing of postexercise carbohydrate-protein ingestion on selected immune indices

Costa, R. J. S., Oliver, S. J., Laing, S. J., Walters, R., Bilzon, J. L. J. & Walsh, N. P., 1 Jan 2009, In : International Journal of Sport Nutrition and Exercise Metabolism. 19, 4, p. 366-384 19 p.

Research output: Contribution to journalArticle

36 Citations (Scopus)