Substance use and mental health disorders are major contributors to the global burden of disease, and their negative impact on human health is rising. In order to address these pressing issues, we need to understand the causes of these problems, their complex interplay, and how to help people affected by them. The Addiction and Mental Health Group (AIM) conducts research on addiction and mental health using state-of-the-art experimental, epidemiological and clinical methods. By triangulating information across these interdisciplinary research themes, we seek evidence that is both robust and relevant for people and society.