Research output per year
Research output per year
- 1 - 50 out of 77 results
Search results
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2024
α-Methylacyl-CoA racemase from Mycobacterium tuberculosis - Detailed Kinetic and Structural Characterization of the Active site
Mojanaga, O., Woodman, T., Lloyd, M. & Acharya, R., 31 Mar 2024, In: Biomolecules. 14, 3, 15 p., 299.Research output: Contribution to journal › Article › peer-review
Open Access -
2023
Analysis of enzyme reactions using NMR techniques: A case study with α-methylacyl-CoA racemase (AMACR)
Woodman, T. & Lloyd, M., 19 Oct 2023, Modern Methods of Drug Design and Development. Lloyd, M. (ed.). New York, U. S. A.: Elsevier Academic Press Inc, p. 159-209 51 p. (Methods in Enzymology; vol. 690).Research output: Chapter or section in a book/report/conference proceeding › Chapter or section
2 Citations (SciVal) -
Synthesis and Antagonist Activity of Methyllycaconitine Analogues on Human α7 Nicotinic Acetylcholine Receptors
Qasem, A. M. A., Rowan, M. G., Sanders, V. R., Millar, N. S. & Blagbrough, I. S., 19 Apr 2023, In: ACS Bio and Med Chem Au. 3, 2, p. 147-157 11 p.Research output: Contribution to journal › Article › peer-review
Open Access5 Citations (SciVal) -
Understanding Rh-catalysed Hydroformylation with Phosphite Ligands through Catalyst Speciation Analysis by Operando FlowNMR Spectroscopy
Bara-Estaún, A., Lyall, C. L., Lowe, J. P., Pringle, P. G., Kamer, P. C. J., Franke, R. & Hintermair, U., 20 Feb 2023, In: ChemCatChem. 15, 4, e202201204.Research output: Contribution to journal › Article › peer-review
Open Access11 Citations (SciVal) -
2022
Atomic-scale characterisation of sodium aluminosilicate hydrates (N-A-S-H) and Mg-substituted N(-M)-A-S-H using XANES
Ke, X., Li, J., Baki, V., Large, A. & Held, G., 31 Dec 2022, In: Applied Geochemistry. 147, 105515.Research output: Contribution to journal › Article › peer-review
Open Access4 Citations (SciVal) -
Synthesis of a tetraphenyl-substituted dihydropentalene and its alkali metal hydropentalenide and pentalenide complexes
Boyt, S. M., Jenek, N. A., Sanderson, H. J., Kociok-Kohn, G. & Hintermair, U., 14 Feb 2022, In: Organometallics. 41, 3, p. 211-225 15 p.Research output: Contribution to journal › Article › peer-review
Open Access8 Citations (SciVal) -
2021
Ambient base-free glycerol oxidation over bimetallic PdFe/SiO2 by in situ generated active oxygen species
Underhill, R., Douthwaite, M., Lewis, R. J., Miedziak, P. J., Armstrong, R. D., Morgan, D. J., Freakley, S. J., Davies, T., Folli, A., Murphy, D. M., He, Q., Akdim, O., Edwards, J. K. & Hutchings, G. J., 31 Jan 2021, In: Research on Chemical Intermediates. 47, 1, p. 303-324 22 p.Research output: Contribution to journal › Article › peer-review
Open Access6 Citations (SciVal) -
A molecular communication channel consisting of a single reversible chain of hydrogen bonds in a conformationally flexible oligomer
Morris, D. T. J., Wales, S. M., Tilly, D. P., Farrar, E. H. E., Grayson, M. N., Ward, J. W. & Clayden, J., 9 Sept 2021, In: Chem. p. 2460-2472Research output: Contribution to journal › Article › peer-review
Open AccessFile23 Citations (SciVal)59 Downloads (Pure) -
Electrodeposition of tin onto a silver textile electrode for Barbier-type electro-organic synthesis of homoallylic alcohols
Karuppusamy, S., Marken, F. & Kulandainathan, M. A., 30 Jun 2021, In: Surfaces and Interfaces. 24, 101085.Research output: Contribution to journal › Article › peer-review
1 Citation (SciVal) -
Prevention and treatment of fungal skin infections using cationic polymeric films
Ho, K. H., Bolhuis, A. & Delgado-Charro, B., 28 Jul 2021, In: Pharmaceutics. 13, 8, 19 p., 1161.Research output: Contribution to journal › Article › peer-review
Open Access1 Citation (SciVal) -
Small Molecule CD38 Inhibitors: Synthesis of 8-Amino-N1-Inosine 5'-Monophosphate, Analogues and Early Structure-Activity Relationship
Watt, J. M., Graeff, R. & Potter, B. V. L., 1 Dec 2021, In: Molecules. 26, 23, 7165.Research output: Contribution to journal › Article › peer-review
Open AccessFile82 Downloads (Pure) -
Structural Studies of Norditerpenoid Alkaloids: Conformation Analysis in Crystal and in Solution States
Zeng, Z., Kociok-Kohn, G., Woodman, T., Rowan, M. & Blagbrough, I., 22 Apr 2021, In: European Journal of Organic Chemistry. 2021, 15, p. 2169-2179 12 p.Research output: Contribution to journal › Article › peer-review
Open Access5 Citations (SciVal) -
Thermodynamic properties of sodium aluminosilicate hydrate (N-A-S-H)
Walkley, B., Ke, X., Hussein, O. & Provis, J. L., 21 Oct 2021, In: Dalton Transactions. 50, 39, p. 13968-13984 17 p.Research output: Contribution to journal › Article › peer-review
Open Access18 Citations (SciVal) -
2020
Affinity for the Interface Underpins Potency of Antibodies Operating In Membrane Environments
Rujas, E., Insausti, S., Leaman, D. P., Carravilla, P., González-Resines, S., Monceaux, V., Sánchez-Eugenia, R., García-Porras, M., Iloro, I., Zhang, L., Elortza, F., Julien, J.-P., Saéz-Cirión, A., Zwick, M. B., Eggeling, C., Ojida, A., Domene, C., Caaveiro, J. M. M. & Nieva, J. L., 18 Aug 2020, In: Cell Reports. 32, 7, 108037.Research output: Contribution to journal › Article › peer-review
Open Access10 Citations (SciVal) -
Impacts of Steric Compression, Protonation, and Intramolecular Hydrogen Bonding on the 15N NMR Spectroscopy of Norditerpenoid Alkaloids and Their Piperidine-Ring Analogues
Zeng, Z., Qasem, A. M. A., Woodman, T. J., Rowan, M. G. & Blagbrough, I. S., 16 Jun 2020, In: ACS OMEGA. 5, 23, p. 14116-14122 7 p.Research output: Contribution to journal › Article › peer-review
Open Access9 Citations (SciVal) -
Incorporation of strontium and calcium in geopolymer gels
Walkley, B., Ke, X., Hussein, O. H., Bernal, S. A. & Provis, J. L., 15 Jan 2020, In: Journal of Hazardous Materials. 382, 121015.Research output: Contribution to journal › Article › peer-review
Open Access83 Citations (SciVal) -
Ligand and Solvent Selection for Enhanced Separation of Palladium Catalysts by Organic Solvent Nanofiltration
Shen, J., Beale, K., Amura, I. & Emanuelsson, E. A. C., 5 May 2020, In: Frontiers in Chemistry. 8, 375.Research output: Contribution to journal › Article › peer-review
Open Access9 Citations (SciVal) -
Synthesis of phosphonoacetate analogues of the second messenger adenosine 5'-diphosphate ribose (ADPR)
Potter, B., Watt, J. M. & Baszczynski, O., 2020, In: RSC Advances. 10, 3, p. 1776-1785Research output: Contribution to journal › Article › peer-review
Open Access6 Citations (SciVal) -
Ti(IV)-Tris(phenolate) Catalyst Systems for the Ring-Opening Copolymerization of Cyclohexene Oxide and Carbon Dioxide
Raman, S. K., Deacy, A. C., Pena Carrodeguas, L., Reis, N. V., Kerr, R. W. F., Phanopoulos, A., Morton, S., Davidson, M. G. & Williams, C. K., 11 May 2020, In: Organometallics. 39, 9, p. 1619–1627Research output: Contribution to journal › Article › peer-review
Open Access22 Citations (SciVal) -
2019
Identification of novel small-molecule inhibitors of α-methylacyl-CoA racemase (AMACR; P504S) and structure-activity relationships
Petrova, Y., Wadda, K., Nathubhai, A., Jevglevskis, M., Mitchell, P., James, T., Threadgill, M., Woodman, T. & Lloyd, M., 1 Nov 2019, In: Bioorganic Chemistry. 92, 103264.Research output: Contribution to journal › Article › peer-review
Open AccessFile12 Citations (SciVal)132 Downloads (Pure) -
Novel 2-arylthiopropanoyl-CoA inhibitors of α-methylacyl-CoA racemase 1A (AMACR; P504S) as potential anti-prostate cancer agents
Jevglevskis, M., Nathubhai, A., Wadda, K., Lee, G. L., Al-Rawi, S., Jiao, T., Mitchell, P., James, T., Threadgill, M., Woodman, T. & Lloyd, M., 1 Nov 2019, In: Bioorganic Chemistry. 92, 103263.Research output: Contribution to journal › Article › peer-review
Open AccessFile10 Citations (SciVal)257 Downloads (Pure) -
The Direct Synthesis of H2O2 and Selective Oxidation of Methane to Methanol Using HZSM-5 Supported AuPd Catalysts
Lewis, R. J., Bara-Estaun, A., Agarwal, N., Freakley, S. J., Morgan, D. J. & Hutchings, G. J., 1 Nov 2019, In: Catalysis Letters. 149, 11, p. 3066-3075 10 p.Research output: Contribution to journal › Article › peer-review
Open Access34 Citations (SciVal) -
2018
Bipyrrolidine salan alkoxide complexes of lanthanides: synthesis, characterisation, activity in the polymerisation of lactide and mechanistic investigation by DOSY NMR
Beament, J., Kociok-Kohn, G., Jones, M. & Buchard, A., 2018, In: Dalton Transactions . 47, p. 9164-9172 9 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile8 Citations (SciVal)99 Downloads (Pure) -
Elucidating lithium-ion and proton dynamics in anti-perovskite solid electrolytes
Dawson, J., Attari, T. S., Chen, H., Emge, S. P., Johnston, K. E. & Islam, M., 1 Oct 2018, In: Energy & Environmental Science. 11, 10, p. 2993-3002 10 p.Research output: Contribution to journal › Article › peer-review
Open Access99 Citations (SciVal)3 Downloads (Pure) -
Structure-activity relationships of rationally designed AMACR 1A inhibitors
Jevglevskis, M., Lee, G. L., Nathubhai, A., Petrova, Y., James, T., Threadgill, M., Woodman, T. & Lloyd, M., 1 Sept 2018, In: Bioorganic and Medicinal Chemistry. 79, p. 145-154 10 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile9 Citations (SciVal)101 Downloads (Pure) -
Synthetic cADPR analogues may form only one of two possible conformational diastereoisomers
Watt, J. M., Thomas, M. & Potter, B., 15 Oct 2018, In: Scientific Reports. 8, 15268.Research output: Contribution to journal › Article › peer-review
Open Access3 Citations (SciVal) -
Well-Defined Heterobimetallic Reactivity at Unsupported Ruthenium-Indium Bonds
Riddlestone, I., Rajabi, N., Macgregor, S., Mahon, M. & Whittlesey, M., 1 Feb 2018, In: Chemistry - A European Journal. 24, 7, p. 1732-1738 7 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile14 Citations (SciVal)66 Downloads (Pure) -
2017
A convenient colorimetric assay for α-methylacyl-CoA racemase (AMACR; P504S) and testing of inhibitors
Jevglevskis, M., Lee, G. L., Nathubhai, A., James, T., Threadgill, M., Woodman, T. & Lloyd, M., 21 Apr 2017, (Unpublished).Research output: Contribution to conference › Abstract › peer-review
File75 Downloads (Pure) -
A novel colorimetric assay for α-methylacyl-CoA racemase 1A (AMACR; P504S) utilizing the elimination of 2,4-dinitrophenolate
Jevglevskis, M., Lee, G. L., Nathubhai, A., Petrova, Y., James, T., Threadgill, M., Woodman, T. & Lloyd, M., 7 May 2017, In: Chemical Communications. 53, 37, p. 5087-5090 4 p.Research output: Contribution to journal › Article › peer-review
Open Access17 Citations (SciVal) -
Endolysosomal targeting of a clinical chlorin photosensitiser for light-triggered delivery of nano-sized medicines
Yaghini, E., Dondi, R., Tewari, K. M., Loizidou, M., Eggleston, I. M. & MacRobert, A. J., 1 Dec 2017, In: Scientific Reports. 7, 1, 6059.Research output: Contribution to journal › Article › peer-review
Open Access26 Citations (SciVal) -
High-Throughput Screening to identify novel inhibitors of human α-methylacyl-CoA racemase 1A (AMACR; P504S)
Petrova, Y., Mattan, H., Lee, G. L., Jevglevskis, M., Woodman, T. & Lloyd, M., 21 Apr 2017.Research output: Contribution to conference › Poster › peer-review
File59 Downloads (Pure) -
Ligand induced activation of human TRPM2 requires the terminal ribose of ADPR and involves Arg 1433 and Tyr 1349
Fliegert, R., Watt, J. M., Schöbel, A., Rozewitz, M. D., Moreau, C., Kirchberger, T., Thomas, M. P., Sick, W., Araujo, A. C., Harneit, A., Potter, B. V. L. & Guse, A. H., 16 Jun 2017, In: Biochemical Journal. 474, 13, p. 2159-2175 BCJ20170091.Research output: Contribution to journal › Article › peer-review
Open Access30 Citations (SciVal) -
Methods (amacr)
Lloyd, M. (Inventor), Jevglevskis, M. (Inventor), Lee, G. L. (Inventor), Woodman, T. (Inventor) & Threadgill, M. (Inventor), 22 Jun 2017, Patent No. US20170176436 A1, Priority date 3 Feb 2014Research output: Patent
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Synthesis and characterization of phosphorescent two coordinate copper(I) complexes bearing diamidocarbene ligands
Shi, S., Collins, L., Mahon, M., Djurovich, P., Thompson, M. & Whittlesey, M., 17 Jan 2017, In: Dalton Transactions . 46, 3, p. 745-752Research output: Contribution to journal › Article › peer-review
Open AccessFile58 Citations (SciVal)347 Downloads (Pure) -
2016
A convenient colorimetric assay for alpha-methylacyl-CoA racemase (AMACR; P504S) and testing for inhibitors
Jevglevskis, M., Lee, G. L., Nathubhai, A., James, T., Threadgill, M., Woodman, T. & Lloyd, M., 21 May 2016, (Unpublished).Research output: Contribution to conference › Poster
File43 Downloads (Pure) -
A Convenient Colorimetric Assay For Alpha-Methylacyl-CoA Racemase (AMACR; P504S) And Testing Of Inhibitors
Jevglevskis, M., Lee, G. L., Nathubhai, A., Petrova, Y., Threadgill, M., James, T., Woodman, T. & Lloyd, M., Jun 2016.Research output: Contribution to conference › Poster
Open AccessFile60 Downloads (Pure) -
A Convenient Colorimetric Assay for α-Methylacyl-CoA Racemase (AMACR; P504S) and Testing Of Inhibitors
Jevglevskis, M., Lee, G. L., Nathubhai, A., James, T., Threadgill, M., Woodman, T. & Lloyd, M., 27 Apr 2016, (Unpublished).Research output: Contribution to conference › Poster
File66 Downloads (Pure) -
A study on the AMACR catalysed elimination reaction and its application to inhibitor testing
Jevglevskis, M., Lee, G. L., Sun, J., Zhou, S., Sun, X., Kociok-Kohn, G., James, T. D., Woodman, T. J. & Lloyd, M. D., Jan 2016, In: Organic and Biomolecular Chemistry. 14, 2, p. 612-622Research output: Contribution to journal › Article › peer-review
Open AccessFile11 Citations (SciVal)144 Downloads (Pure) -
A Study On The α-Methylacyl-CoA Racemase (AMACR) Elimination Reaction And Its Application To Inhibitor Testing
Jevglevskis, M., Lee, G. L., Sun, J., Zhou, S., Sun, X., Kociok-Kohn, G., James, T., Woodman, T. & Lloyd, M., 27 Apr 2016, (Unpublished).Research output: Contribution to conference › Poster
File85 Downloads (Pure) -
Flexible synthesis of cationic peptide-porphyrin derivatives for light-triggered drug delivery and photodynamic therapy
Dondi, R., Yaghini, E., Tewari, K. M., Liguo, W., Giuntini, F., Loizidou, M., MacRobert, S. & Eggleston, I., 14 Nov 2016, In: Organic and Biomolecular Chemistry. 14, p. 11488-11501 13 p.Research output: Contribution to journal › Article › peer-review
Open Access28 Citations (SciVal) -
Lactide polymerisation by ring-expanded NHC complexes of zinc
Collins, L. R., Mofffat, L. A., Mahon, M. F., Jones, M. D. & Whittlesey, M. K., 8 Jan 2016, In: Polyhedron. 103, Part A, p. 121-125Research output: Contribution to journal › Article › peer-review
Open AccessFile18 Citations (SciVal)262 Downloads (Pure) -
Methods (AMACR)
Lloyd, M. (Inventor), Jevglevskis, M. (Inventor), Lee, G. L. (Inventor), Woodman, T. (Inventor) & Threadgill, M. (Inventor), 14 Dec 2016, Patent No. EP3102694 A1, Priority date 3 Feb 2014Research output: Patent
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The Influence of ring-expanded N-heterocyclic carbenes on the structures of half-sandwich Ni(I) complexes: an X-ray, EPR, and ENDOR study
Pelties, S., Carter, E., Folli, A., Mahon, M., Murphy, D., Whittlesey, M. & Wolf, R., 7 Nov 2016, In: Inorganic Chemistry. 55, p. 11006-11017Research output: Contribution to journal › Article › peer-review
Open AccessFile28 Citations (SciVal)196 Downloads (Pure) -
2015
A Convenient Colorimetric Assay for α-Methylacyl-CoA Racemase (AMACR; P504S) and Testing Of Inhibitors
Jevglevskis, M., Lee, G. L., Nathubhai, A., James, T., Threadgill, M., Woodman, T. & Lloyd, M., 11 Nov 2015, (Unpublished).Research output: Contribution to conference › Poster
File72 Downloads (Pure) -
A Study On The α-Methylacyl-CoA Racemase (AMACR) Elimination Reaction And Its Application To Inhibitor Testing
Jevglevskis, M., Lee, G. L., Sun, J., Zhou, S., Sun, X., Kociok-Kohn, G., James, T., Woodman, T. & Lloyd, M., 11 Nov 2015, (Unpublished).Research output: Contribution to conference › Poster
File61 Downloads (Pure) -
Methods (AMACR).
Lloyd, M. (Inventor), Woodman, T. (Inventor), Jevglevskis, M. (Inventor), Threadgill, M. (Inventor) & Lee, G. L. (Inventor), 6 Aug 2015, IPC No. C12Q1/533, G01N33/574, Patent No. WO2015114383A1, 2 Feb 2015, Priority date 3 Feb 2014, Priority No. GB201401817AResearch output: Patent
File53 Downloads (Pure) -
New routes to fight castrate-resistant prostate cancer: targeting α-methylacyl-CoA racemase (AMACR)
Lee, G. L., Jevglevskis, M., Woodman, T. & Lloyd, M., 2015, (Unpublished).Research output: Contribution to conference › Poster
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New routes to fight castrate-resistant prostate cancer: targeting α-methylacyl-CoA racemase (AMACR)
Lee, G. L., Jevglevskis, M., Threadgill, M., Woodman, T. & Lloyd, M., 2015, (Unpublished).Research output: Contribution to conference › Poster
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New routes to fight castrate-resistant prostate cancer: targeting α-methylacyl-CoA racemase (AMACR)
Lee, G. L., Jevglevskis, M., Threadgill, M., Woodman, T. & Lloyd, M., 2015, (Unpublished).Research output: Contribution to conference › Poster
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2014
A hydrazide-anchored dendron scaffold for chemoselective ligation strategies
O'Donovan, L. & De Bank, P., 7 Oct 2014, In: Organic and Biomolecular Chemistry. 12, 37, p. 7290-7296 7 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile5 Citations (SciVal)197 Downloads (Pure)