Dataset for 'Pre-Exercise Breakfast Ingestion versus Extended Overnight Fasting Increases Postprandial Glucose Flux after Exercise in Healthy Men: Pre-exercise feeding and postprandial glucose flux'

Dataset

Description

The aim of this study was to characterise postprandial glucose flux after exercise in the fed versus overnight fasted-state and to investigate potential underlying mechanisms. In a randomized order, twelve men underwent breakfast-rest (BR; 3 h semi-recumbent), breakfast-exercise (BE; 2 h semi-recumbent before 60-min of cycling (50% peak power output) and overnight fasted-exercise (FE; as per BE omitting breakfast) trials. An oral glucose tolerance test (OGTT) was completed post-exercise (post-rest on BR). Dual stable isotope tracers ([U-13C] glucose ingestion and [6,6-2H2] glucose infusion) and muscle biopsies were combined to assess postprandial plasma glucose kinetics and intramuscular signaling, respectively. Plasma intestinal fatty acid binding (I-FABP) concentrations were determined as a marker of intestinal damage. The results from this study showed that consuming breakfast before exercise increases post-exercise postprandial plasma glucose disposal, which is offset (primarily) by increased appearance rates of orally-ingested glucose. Therefore, metabolic responses to fed-state exercise cannot be readily inferred from studies conducted in a fasted state.
Date made available27 Feb 2019
PublisherUniversity of Bath

Cite this

Edinburgh, R. (Creator), Hengist, A. (Creator), Smith, H. (Creator), Travers, R. (Creator), Koumanov, F. (Creator), Betts, J. (Creator), Thompson, D. (Creator), Walhin, J. (Creator), Wallis, G. (Creator), Hamilton, D. L. (Creator), Stevenson, E. (Creator), Tipton, K. (Creator), Gonzalez, J. (Creator) (27 Feb 2019). Dataset for 'Pre-Exercise Breakfast Ingestion versus Extended Overnight Fasting Increases Postprandial Glucose Flux after Exercise in Healthy Men: Pre-exercise feeding and postprandial glucose flux'. University of Bath. 10.15125/BATH-00608