Dataset for Hollow-fiber membrane technology: Characterization and proposed use as a potential mimic of skin vascularization towards the development of a novel skin absorption in vitro model



This dataset contains data collected using capillary bed bioreactor (CBB), a new method for pseudovascularisation of skin models. The data was collected by sampling the permeate that exited the fibres, and the amount of caffeine in the samples was measured using HPLC for the purpose of assessing permeability. By observing and analyzing the data we can conclude that the new bioreactor will be more physiologically accurate than the current model and can therefore potentially refine inputs to our mechanistic models for skin sensitisation, to give us more accurate predictions of adverse outcomes. The data is organised in an Excel spreadsheet with each tab relating to a specific figure in the paper.
Date made available30 Jan 2019
PublisherUniversity of Bath
Date of data production1 Oct 2014 - 30 Jun 2016

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