Description
This dataset pertains to a study involving the use of 3D printed microneedles (MNs) to form hydrogel-forming MNs (HFMs) for the delivery of antibiotics (amoxicillin and vancomycin) transdermally. It includes:
- the HFMs ability to swell in fluids over time rapidly and take up drugs in solution as a result (including characterisation of the HFMs and drug loaded-HFMs);
- the mechanical properties and skin penetration of both HFMs and Drug-loaded HFMs;
- the drug release profiles of the drug-loaded HFMs and how to control the release;
- the antimicrobial properties of the antibiotic HFMs against susceptible bacteria.
The data provides a suggestion towards the use of HFMs for the effective transdermal delivery of antibiotics, towards reducing the rate of antimicrobial resistance increase.
- the HFMs ability to swell in fluids over time rapidly and take up drugs in solution as a result (including characterisation of the HFMs and drug loaded-HFMs);
- the mechanical properties and skin penetration of both HFMs and Drug-loaded HFMs;
- the drug release profiles of the drug-loaded HFMs and how to control the release;
- the antimicrobial properties of the antibiotic HFMs against susceptible bacteria.
The data provides a suggestion towards the use of HFMs for the effective transdermal delivery of antibiotics, towards reducing the rate of antimicrobial resistance increase.
| Date made available | 23 May 2023 |
|---|---|
| Publisher | University of Bath |
Research output
- 1 Article
-
Antimicrobial releasing hydrogel forming microneedles
Turner, J., Laabei, M., Li, S., Estrela, P. & Leese, H., 31 Aug 2023, In: Biomaterials Advances. 151, 11 p., 213467.Research output: Contribution to journal › Article › peer-review
Open Access29 Link opens in a new tab Citations (SciVal)
Student theses
-
Detect, Tell, and Treat: Microneedle Skin Patches to Sense and Treat Infection: (Alternative Format Thesis)
Turner, J. (Author), Leese, H. (Supervisor) & Estrela, P. (Supervisor), 13 Sept 2023Student thesis: Doctoral Thesis › PhD
File
Projects
- 2 Finished
-
Minimally Invasive Molecularly Imprinted Conductive Nanoneedle Sensors
Leese, H. (PI)
Engineering and Physical Sciences Research Council
1/04/21 → 31/07/23
Project: Research council
-
Molecularly Imprinted Conductive Microneedles
Leese, H. (PI)
31/03/20 → 30/03/22
Project: Research council
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