Description

This dataset pertains to a study involving the use of 3D printed microneedles (MNs) to form hydrogel-forming MNs (HFMs) for the delivery of antibiotics (amoxicillin and vancomycin) transdermally. It includes:

- the HFMs ability to swell in fluids over time rapidly and take up drugs in solution as a result (including characterisation of the HFMs and drug loaded-HFMs);
- the mechanical properties and skin penetration of both HFMs and Drug-loaded HFMs;
- the drug release profiles of the drug-loaded HFMs and how to control the release;
- the antimicrobial properties of the antibiotic HFMs against susceptible bacteria.

The data provides a suggestion towards the use of HFMs for the effective transdermal delivery of antibiotics, towards reducing the rate of antimicrobial resistance increase.
Date made available23 May 2023
PublisherUniversity of Bath

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